Ventral Premotor-Motor Cortex Interactions in the Macaque Monkey during Grasp: Response of Single Neurons to Intracortical Microstimulation
Ventral Premotor-Motor Cortex Interactions in the Macaque Monkey during Grasp: Response of Single Neurons to Intracortical Microstimulation
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DOI：
10.1523/jneurosci.0525-11.2011
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发表时间：
2011-06-15
影响因子：
5.3
通讯作者：
Brochier, Thomas
中科院分区：
文献类型：
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作者：
Kraskov, Alexander;Prabhu, Gita;Brochier, Thomas
最近对猴子和人类的刺激研究表明，腹侧运动前皮质(F5区)和初级运动皮质(M1)的手部区域之间存在强烈的相互作用。这些短潜伏期的相互作用通常涉及从M1的F5输出到手部肌肉的易化，尽管也有报道抑制。这项研究在三只清醒的猕猴身上进行，旨在寻找证据表明，这些相互作用可能是由抓握任务中活跃的单个M1神经元的短潜伏期兴奋性和抑制性反应所介导的。我们记录了这些M1神经元对单个低阈值(
Recent stimulation studies in monkeys and humans have shown strong interactions between ventral premotor cortex (area F5) and the hand area of primary motor cortex (M1). These short-latency interactions usually involve facilitation from F5 of M1 outputs to hand muscles, although suppression has also been reported. This study, performed in three awake macaque monkeys, sought evidence that these interactions could be mediated by short-latency excitatory and inhibitory responses of single M1 neurons active during grasping tasks. We recorded responses of these M1 neurons to single low-threshold (