Altered burst responses in hippocampal CA3 neurons injected with EGTA.

Altered burst responses in hippocampal CA3 neurons injected with EGTA.
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注射 EGTA 改变海马 CA3 神经元的突发反应。

DOI:
10.1007/bf00237513
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发表时间:
1981
影响因子:
2
通讯作者:
Hablitz,JJ
Hablitz,JJ
中科院分区:
医学4区
文献类型:
--
作者:
Hablitz,JJ

文献摘要

相似文献

细胞内注射EGTA可消除海马CA3神经元自发和诱发的动作电位爆发后的超极化。同时记录,正交诱导ipsp相对不受这种处理的影响。CA3神经元产生至少两种类型的超极化:一种是由钙介导的钾电导引起的,另一种是由对氯的电导增加引起的。
Intracellular injection of EGTA abolished the hyperpolarization seen after spontaneous and evoked bursts of action potentials in hippocampal CA3 neurons. Simultaneously recorded, orthodromically elicited IPSPs were relatively unaffected by this treatment. It is concluded that CA3 neurons generate at least two types of hyperpolarization: one resulting from a calcium-mediated potassium conductance and the other from increased conductance to chloride.