Sequence Analysis of the S10 Gene of Six Bluetongue Virus Isolates from India
Sequence Analysis of the S10 Gene of Six Bluetongue Virus Isolates from India
复制标题
DOI：
10.1111/j.1865-1682.2009.01089.x
复制
发表时间：
2009-10-01
影响因子：
4.3
通讯作者：
Mondal, B.
中科院分区：
文献类型：
--
作者：
Desai, G. S.;Hosamane, M.;Mondal, B.
基于蓝舌病毒（BTV）基因组片段10（S10）的系统发育研究对于理解BTV的进化具有重要意义。基于S10基因的系统发育分析将来自印度的6个不同BTV分离株（BTV血清型1、18和23）归类在亚支A1中，并显示与来自地中海盆地的BT病毒的关系更近。印度BTV血清型18和23形成了与BTV血清型1分离株不同的单个簇，并且是从来自中国、印度尼西亚和澳大利亚的BTV进化而来的。印度BTV分离株的S10序列基本保守（同源性>95.7%），与世界上其他BT病毒不同。
Bluetongue Virus (BTV) genome segment 10 (S10)-based phylogenetic studies are important in understanding the BTV evolution. S10 gene-based phylogenetic analysis grouped six different BTV isolates (BTV serotype 1, 18 and 23) from India in subclade A1 and showed closer relationship with BT viruses from Mediterranean Basin. Indian BTV serotypes 18 and 23 formed a single cluster distinct from BTV serotype 1 isolates and were evolved from BTV from China, Indonesia and Australia. The overall S10 sequences of BTV isolates from India were largely conserved (>95.7% homology) and were distinct from other BT viruses of the world.