Optical Coherence Tomography-Based Angiography in Retinal Artery Occlusion in Children
Optical Coherence Tomography-Based Angiography in Retinal Artery Occlusion in Children
复制标题
基于光学相干断层扫描的血管造影在儿童视网膜动脉阻塞中的应用
DOI：
10.1159/000484351
复制
发表时间：
2018
影响因子：
2.1
通讯作者：
Agnieszka Czeszyk
中科院分区：
文献类型：
--
作者：
W. Hautz;J. Gołębiewska;Agnieszka Czeszyk
目的：评价基于光学相干断层扫描（OCT）的血管造影（OCTA）在儿童视网膜动脉阻塞（RAO）诊断和监测中的作用。材料和方法：这项回顾性研究于2015年3月至2016年5月在华沙儿童纪念健康研究所眼科进行。所有患者均接受了完整的眼科检查。眼底检查和荧光素血管造影（FA）是诊断该病的基础。在基线和每次随访访视时进行OCT和OCTA。结果：4例（4只眼）RAO患者（2男2女，年龄8-16岁）入组研究。在所有病例中，初始OCTA图像均显示了浅表和深部视网膜毛细血管丛的典型缺血性变化。随访OCTA显示RAO区域缺血面积增加，动脉持续狭窄。在OCTA图像上可以看到由于缺血导致的毛细血管网络的损失和更暗、更光滑的背景。结论：OCTA可以清晰地显示RAO儿童视网膜血管灌注的进行性损害，可能是标准FA的替代方法。需要进一步的研究来证实我们的结果，并确定OCTA在儿科患者中的作用。
Purpose: To evaluate the role of optical coherence tomography (OCT)-based angiography (OCTA) in the diagnosis and monitoring of pediatric patients with retinal artery occlusion (RAO). Material and Methods: This retrospective study was conducted at the Department of Ophthalmology, The Children's Memorial Health Institute, in Warsaw between March 2015 and May 2016. Every patient underwent a complete ophthalmological examination. The diagnosis of the disease was based on fundus examination and fluorescein angiography (FA). OCT and OCTA were performed at baseline and every follow-up visit. Results: Four patients (4 eyes) (2 boys/2 girls, age 8-16 years) with RAO were enrolled in the study. In all cases, initial OCTA images revealed typical ischemic changes in superficial and deep retinal capillary plexuses. Follow-up OCTA revealed increasing areas of ischemia in the RAO region and persistent narrowing of the arteries. The loss of capillary network and the darker, smooth background due to ischemia were visible on OCTA images. Conclusions: OCTA enables clear visualization of progressive impairment of the retinal vascular perfusion in children with RAO and may be an alternative to the standard FA. Further studies are needed to confirm our results and establish the role of OCTA in pediatric patients.