Long-range attraction of particles adhered to lipid vesicles
Long-range attraction of particles adhered to lipid vesicles
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DOI：
10.1103/physreve.94.012604
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发表时间：
2016-07-05
影响因子：
2.4
通讯作者：
Dufresne, Eric R.
中科院分区：
文献类型：
--
作者：
Sarfati, Raphael;Dufresne, Eric R.
许多生物系统将脂质膜的薄片折叠成复杂的三维结构。这种微观折纸通常由蛋白质在膜上的吸附和自组装介导。作为研究吸附介导的相互作用的模型系统，我们研究了粘附在脂质囊泡上的微米颗粒的集体行为。我们估计胶体的相互作用，使用粒子轨迹的最大似然分析。当粒子被一个张力膜高度包裹时，我们观察到强烈的长程吸引力，典型的结合能为150 k（B）T，并且显著的力延伸到几微米。
Many biological systems fold thin sheets of lipid membrane into complex three-dimensional structures. This microscopic origami is often mediated by the adsorption and self-assembly of proteins on a membrane. As a model system to study adsorption-mediated interactions, we study the collective behavior of micrometric particles adhered to a lipid vesicle. We estimate the colloidal interactions using a maximum likelihood analysis of particle trajectories. When the particles are highly wrapped by a tense membrane, we observe strong long-range attractions with a typical binding energy of 150k(B)T and significant forces extending a few microns.