Diabetes in Non-Hispanic White Youth Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
Diabetes in Non-Hispanic White Youth Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
复制标题
DOI：
10.2337/dc09-s202
复制
发表时间：
2009-03-01
期刊：
影响因子：
16.2
通讯作者：
Dabelea, Dana
中科院分区：
文献类型：
--
作者：
Bell, Ronny A.;Mayer-Davis, Elizabeth J.;Dabelea, Dana
目的-调查美国非西班牙裔白色（NHW）青年糖尿病的发病率，患病率和临床特征。研究设计和方法-数据来自青年糖尿病研究中心（NHW研究），一个多中心研究0-19岁青年糖尿病。计算了4个发病年（2002-2005年）的发病率/100，000人-年，并计算了2001年的患病率/1，000名青年。通过问卷调查，体检，血液和尿液收集获得的信息进行了分析，以描述谁完成了一个人visit.RESULTS -1型糖尿病（在0-19岁）的患病率为2.00/1000，这是男性（2.02/1000）和女性（1.97/1000）受试者的特点。I型糖尿病的发病率为23.6/100，000，男性略高于女性（分别为24.5/100，000和22.7/100，000，P = 0.04）。在这项研究中，0-14岁青少年I型糖尿病的发病率高于所有先前报道的美国研究和许多欧洲研究。少数情况下2型糖尿病的青年年龄40%有升高的低密度脂蛋白胆固醇，和10年满足目前的建议摄入饱和脂肪。在年龄≥ 15岁的青年中，1.8%的I型糖尿病患者和26%的2型糖尿病患者是当前吸烟者。美国NHW青年中I型糖尿病的发病率是世界上最高的。虽然2型糖尿病仍然相对罕见，但发病率比欧洲国家报告的高出数倍。我们认为，努力改善这一人群的心脏代谢和行为风险因素是有必要的。糖尿病护理32（增刊2）：S102-S111，2009年
OBJECTIVE - To investigate the incidence, prevalence, and clinical characteristics of diabetes among U.S. non-Hispanic white (NHW) youth.RESEARCH DESIGN AND METHODS - Data from the SEARCH for Diabetes in Youth Study (SEARCH study), a multicenter study of diabetes among youth aged 0-19 years, were examined. Incidence rates were calculated per 100,000 person-years across 4 incident years (2002-2005), and prevalence in 2001 was calculated per 1,000 youths. Information obtained by questionnaire, physical examination, and blood and urine Collection was analyzed to describe the characteristics of youth who completed an in-person visit.RESULTS - The prevalence of type 1 diabetes (at ages 0-19 years) was 2.00/1,000, which was similar for male (2.02/1,000) and female (1.97/1,000) Subjects. The incidence of type I diabetes was 23.6/100,000, slightly higher for male compared with female subjects (24.5 vs. 22.7 per 100,000, respectively, P = 0.04). Incidence rates of type I diabetes among youth aged 0-14 years in the SEARCH study are higher than all previously reported U.S. Studies and many European studies. Few cases Of type 2 diabetes in youth aged 40% had elevated LDL cholesterol, and 10 years met current recommendations for intake of saturated fat. Among youth aged >= 15 years, 1.8% with type I and 26% with type 2 diabetes were current smokers.CONCLUSIONS - The SEARCH study is one of the most comprehensive studies of diabetes in NHW youth. The incidence of type I diabetes in NHW youth in the U.S. is one of the highest in the world. While type 2 diabetes is still relatively rare, rates are several-fold higher than those reported by European countries. We believe efforts directed at improving the cardiometabolic and behavioral risk factor profiles in this population are warranted. Diabetes Care 32 (Suppl. 2):S102-S111, 2009