Prognostic factors related with survival in patients with pancreatic adenocarcinoma
Prognostic factors related with survival in patients with pancreatic adenocarcinoma
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DOI：
10.3748/wjg.v20.i31.10802
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发表时间：
2014-08-21
影响因子：
4.3
通讯作者：
Bilici, Ahmet
中科院分区：
文献类型：
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作者：
Bilici, Ahmet
胰腺癌患者的预后很差，并且这种癌症是全球癌症相关死亡的第四大原因。虽然手术切除是胰腺癌唯一的根治性治疗选择，但大多数患者被诊断为晚期，因此只有10%-15%的患者适合根治性切除，总生存率不到5%。转移性肿瘤的化疗是为了减轻患者的症状，提高生存率。因此，预后因素是重要的，正确定义预后不良因素可能有助于指导胰腺癌患者更积极的辅助或积极的治疗方案。本文就近年来影响胰腺癌患者生存的因素进行综述。(C)2014百世登出版集团股份有限公司All rights reserved.
The prognosis in patients with pancreatic cancer is poor and this cancer is the fourth leading cause of cancer-related death worldwide. Although surgical resection is the only curative treatment of choice for pancreatic cancer, the majority of patients are diagnosed at an advanced stage, thus only 10%-15% of them are suitable for curative resection and the overall survival is less than 5%. Chemotherapy for metastatic disease is to palliate symptoms of patients and to improve survival. Therefore, prognostic factors are important and a correct definition of poor prognostic factors may help to guide more aggressive adjuvant or aggressive treatment protocols in patients with pancreatic cancer. This article reviews the prognostic factors affecting survival of patients with pancreatic cancer in the light of recent advances in the literature. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.