Uncertainty, mood states, and symptom distress in patients with primary brain tumors: Analysis of a conceptual model using structural equation modeling
Uncertainty, mood states, and symptom distress in patients with primary brain tumors: Analysis of a conceptual model using structural equation modeling
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DOI：
10.1002/cncr.28121
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发表时间：
2013-08-01
期刊：
影响因子：
6.2
通讯作者：
Armstrong, Terri S.
中科院分区：
文献类型：
--
作者：
Lin, Lin;Chiang, Hui-Hsun;Armstrong, Terri S.
背景原发性脑肿瘤（PBT）患者面临与预后、症状、治疗反应和毒性相关的不确定性。本报告的作者研究了患者的不确定性，情绪状态，和symptoms.METHODS之间的直接/间接关系，总共有186例患者与PBT在疾病轨迹的不同点累计。数据收集工具包括一份由医生填写的临床检查表、一份由患者填写的人口统计学数据表、Mishel疾病不确定性量表-脑肿瘤表（MUIS-BT）、MD安德森症状量表-脑肿瘤模块（MDASI-BT）和情绪状态简表（POMS-SF）。结构方程模型被用来探讨变量之间的相关性。结果参与者主要是白色（80%）男性（53%）与各种脑肿瘤。他们的年龄范围为19岁至80岁（平均值+/-标准差，44.2 +/-12.6岁）。较低的功能状态和疾病轨迹中较早的点与更大的不确定性相关（P
BACKGROUND Patients with primary brain tumors (PBTs) face uncertainty related to prognosis, symptoms, treatment response, and toxicity. The authors of this report examined the direct/indirect relations among patients' uncertainty, mood states, and symptoms.METHODS In total, 186 patients with PBTs were accrued at various points in the illness trajectory. Data-collection tools included an investigator-completed clinician checklist, a patient-completed demographic data sheet, the Mishel Uncertainty in Illness Scale-Brain Tumor Form (MUIS-BT), the MD Anderson Symptom Inventory-Brain Tumor Module (MDASI-BT), and the Profile of Mood States-Short Form (POMS-SF). Structural equation modeling was used to explore correlations among variables.RESULTS Participants were primarily white (80%) men (53%) with a variety of brain tumors. They ranged in age from 19 to 80 years (mean +/- standard deviation, 44.2 +/- 12.6 years). Lower functional status and earlier point in the illness trajectory were associated with greater uncertainty (P