Reference values for trabecular and cortical vertebral bone density in single and dual-energy quantitative computed tomography.
Reference values for trabecular and cortical vertebral bone density in single and dual-energy quantitative computed tomography.
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单能和双能定量计算机断层扫描中小梁骨和皮质椎骨密度的参考值。
DOI：
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发表时间：
1989
影响因子：
3.3
通讯作者：
J. Fraga
中科院分区：
文献类型：
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作者：
W. Kalender;D. Felsenberg;O. Louis;P. Lopez;E. Klotz;M. Osteaux;J. Fraga
文献报道的椎体骨密度（BMD）参考值的有效性经常受到质疑。双能量方法、新的校准系统和自动图像评估算法的引入，也使得我们有必要重新评估正常人群的骨密度值。我们介绍了135名男性和139名女性的骨小梁（tBMD）和皮质（cBMD）骨密度的单能量（SEQCT）和双能量定量CT （DEQCT）的患者选择标准、CT测量和评估方案以及结果。对于SEQCT，通过线性回归确定男性和女性的tBMD损失率分别为每年1.7和1.8 mg/ml。各自的DEQCT数据显示，随着年龄的增长，下降幅度较小。对女性骨密度的不同统计模型进行检验；基于tBMD多相变化的模型得到了拟合的改进。cBMD随年龄增长的损失率远小于tBMD；然而，雌性的损失率明显高于雄性。我们的结果与已发表的数据进行了比较。
The validity of reference values for vertebral bone mineral density (BMD) reported in the literature has frequently been questioned. The introduction of dual-energy methods, new calibration systems, and automated image evaluation algorithms, has also made it necessary for us to re-evaluate BMD values in a normal population. We present patient selection criteria, CT measurement and evaluation protocols and results of single energy (SEQCT) and dual energy quantitative CT (DEQCT) for trabecular (tBMD) and cortical (cBMD) bone density in 135 males and 139 females. For SEQCT, tBMD loss rates of 1.7 and 1.8 mg/ml per year for males and females, respectively, were determined by linear regression. The respective DEQCT data show smaller decrements with age. Different statistical models for tBMD in females were tested; models based on a multiphase variation of tBMD yielded an improvement of the fit. For cBMD the percent rate of loss with age is much smaller than for tBMD; females showed a significantly higher loss rate than males, however. A comparison of our results with published data is included.