BIOMECHANICAL PROPERTIES OF KERATOCONUS AND NORMAL CORNEAS
BIOMECHANICAL PROPERTIES OF KERATOCONUS AND NORMAL CORNEAS
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DOI：
10.1016/s0014-4835(80)80027-3
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发表时间：
1980-01-01
影响因子：
3.4
通讯作者：
OXLUND, H
中科院分区：
文献类型：
--
作者：
ANDREASSEN, TT;SIMONSEN, AH;OXLUND, H
单轴抗拉强度测定6圆锥角膜和7正常[人]角膜。在载荷和变形记录期间，在材料试验机中以恒定速度拉伸条带试样。将荷载-变形曲线转化为荷载-应变曲线和应力-应变曲线。从载荷-应变曲线和应力-应变曲线推导出以下参数：最大载荷和应力值以及相应的应变值、最大刚度值以及测试期间样本的相对能量吸收。圆锥角膜组除最大负荷或应力时的应变值外，其余参数均小于正常组。圆锥角膜的载荷和应力值在相应的应变值小于正常角膜的曲线的初始和线性部分。生化方面，两组糖醛酸浓度无差异。羟脯氨酸浓度在两组中无差异。胃蛋白酶处理的胶原蛋白在圆锥角膜中的溶解度大于正常角膜，但溶解度小于肌腱。
The uniaxial tensile strength was determined for 6 keratoconus and 7 normal [human] corneas. Strip specimens were stretched at a constant speed in a materials testing machine during load and deformation recordings. Load-deformation curves were transformed into load-strain and stress-strain curves. The following parameters were derived from the load-strain and stress-strain curves: the maximum load and stress values and the corresponding strain value, the values for maximum stiffness, and the relative energy absorption of the specimens during testing. With the exception of the strain value at maximum load or stress, these parameters were smaller in the keratoconus group than in the normal group. The load and stress values at corresponding strain values were less in keratoconus corneas than in normal corneas for the initial and the linear parts of the curves. Biochemically, no difference was found in the concentration of uronic acid in the 2 groups. No difference was found in the concentration of hydroxyproline in the 2 groups. The solubility of pepsin-treated collagen in the keratoconus corneas was greater than that in the normal corneas, but the solubility was less than that in tendons.