Dynamic Contrast-Enhanced MR Imaging

Dynamic Contrast-Enhanced MR Imaging
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DOI:
10.1097/01.ftd.0000136399.78067.dd
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发表时间:
2004-04
影响因子:
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通讯作者:
G. Shah;N. Fischbein;D. Gandhi;S. Mukherji
G. Shah;N. Fischbein;D. Gandhi;S. Mukherji
中科院分区:
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文献类型:
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作者:
G. Shah;N. Fischbein;D. Gandhi;S. Mukherji

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动态增强磁共振成像是一种有用的临床工具,在评估软组织肿瘤和淋巴结的头部和颈部。它被认为是一个有用的预测头和颈部肿瘤的放射治疗的反应,并用于监测治疗和区分治疗后的变化与复发性肿块更大的信心。它可以用来区分正常和恶性组织,并区分恶性淋巴瘤从其他淋巴结肿大。该技术利用恶性组织和非恶性组织之间微血管和微循环的相对差异,在团注造影剂给药后实现更大的信号成像对比度。本文解释了这种新的诊断工具的基本原理和成像技术。讨论了临床应用和技术挑战。还概述了未来的挑战和结果中的一些矛盾。
Dynamic contrast-enhanced magnetic resonance imaging is a useful clinical tool in evaluation of soft tissue neoplasm and lymph nodes in head and neck. It is thought to be a useful predictor of response to radiotherapy for head and neck carcinoma and used to monitor the treatment and distinguish post-therapeutic changes from recurrent mass with greater confidence. It can be used to distinguish between normal and malignant tissue and to differentiate a malignant lymphoma from other lymph nodal enlargements. The technique utilizes relative differences in microvasculature and microcirculation between malignant and non-malignant tissue to achieve greater contrast in signal imaging following bolus contrast administration. This article explains the underlying principles and imaging techniques for this new diagnostic tool. The clinical applications and technical challenges are discussed. The future challenges and some contradictions in results are also outlined.