A method for endoscopic visualization of rat fetuses in situ.
A method for endoscopic visualization of rat fetuses in situ.
复制标题
一种对大鼠胎儿进行内窥镜原位可视化的方法。
DOI：
10.1016/0031-9384(86)90302-1
复制
发表时间：
1986
影响因子：
2.9
通讯作者：
Robinson,SR
中科院分区：
文献类型：
--
作者：
Smotherman,WP;Robinson,SR
在过去的五年中，出现了几份报告，描述了操纵子宫环境的替代方法[2，11]和观察子宫内大鼠胎儿的行为[5，7，9]。所有采用直接观察胎仔的研究中的一个程序共性是需要将妊娠大鼠的子宫外化，以获得对受试胎仔的视觉访问。相比之下，人类胎儿行为的研究依赖于母体报告或遥感（例如，分娩力测定法，真实的时间超声检查）来监测母体腹部内的胎儿活动[1，3，6]。在这份报告中，我们描述了使用内窥镜光学仪器，允许直接可视化的大鼠胎儿子宫外化。
IN the past five years several reports have appeared describing alternative methods for manipulating the uterine environment [2, 11] and observing the behavior of rat fetuses in utero [5, 7, 9]. A procedural commonality in all studies employing direct observation of fetuses is the necessity to externalize the uterus of the pregnant rat in order to gain visual access to subject fetuses. In contrast, studies of the behavior of human fetuses have relied on maternal reports or remote sensing (eg, tocodynamometry, real time ultrasonography) to monitor fetal activity within the mother's abdomen [1, 3, 6]. In this report, we describe the use of an endoscopic optical instrument that permits direct visualization of rat fetuses without externalization of the uterus.