Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact
Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact
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DOI：
10.1016/j.psyneuen.2010.01.013
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发表时间：
2010-09-01
影响因子：
3.7
通讯作者：
Zagoory-Sharon, Orna
中科院分区：
文献类型：
--
作者：
Feldman, Ruth;Gordon, Ilanit;Zagoory-Sharon, Orna
动物研究表明，神经肽催产素（OT）通过早期的父母照顾机制，特别是母亲的梳理和接触，在父母与婴儿的联系过程中起着关键作用。然而，参与OT在人类养育仍然知之甚少，没有数据可用于OT的作用，在人类父亲的发展，和模式的父母照顾和OT反应之间的联系还没有在人类中进行了探索。112名母亲和父亲与他们4-6个月大的婴儿进行了15分钟的玩耍和接触互动，并对父母触摸的模式进行了微编码。结果显示，母亲和父亲的血浆和唾液OT的基线水平是相似的，血浆和唾液中的OT水平是相互关联的，并且OT与父母特定的触觉接触模式相关。人类母亲谁提供了高水平的深情接触后，母婴互动OT增加，但这种增加没有观察到母亲显示低水平的深情接触。在父亲中，只有那些表现出高水平的刺激性接触表现出OT增加。这些结果表明，在人类父母的相互作用与其他哺乳动物的神经内分泌基础的一致性。研究结果强调，需要提供机会，父亲的照顾，触发父性的生物学基础，并建议，干预措施，允许社会参与可能会建议在减少母婴接触的条件下，如早产或产后抑郁症。(C)2010爱思唯尔有限公司版权所有。
Animal studies have demonstrated that the neuropeptide oxytocin (OT) plays a critical role in processes of parent-infant bonding through mechanisms of early parental care, particularly maternal grooming and contact. Yet, the involvement of OT in human parenting remains poorly understood, no data are available on the role of OT in the development of human fathering, and the links between patterns of parental care and the OT response have not been explored in humans. One hundred and twelve mothers and fathers engaged in a 15-min play-and-contact interaction with their 4-6-month-old infants and interactions were micro-coded for patterns of parental touch. Results showed that baseline levels of plasma and salivary OT in mothers and fathers were similar, OT levels in plasma and saliva were inter-related, and OT was associated with the parent-specific mode of tactile contact. Human mothers who provided high levels of affectionate contact showed an OT increase following mother infant interaction but such increase was not observed among mothers displaying low levels of affectionate contact. Among fathers, only those exhibiting high levels of stimulatory contact showed an OT increase. These results demonstrate consistency in the neuroendocrine basis of human parental interactions with those seen in other mammals. The findings underscore the need to provide opportunities for paternal care to trigger the biological basis of fatherhood and suggest that interventions that permit social engagement may be recommended in conditions of diminished maternal infant contact, such as prematurity or postpartum depression. (C) 2010 Elsevier Ltd. All rights reserved.