Utility of 13N-Ammonia Positron Emission Tomography to Visualize the Therapeutic Effect: A Case With Anteroseptal Myocardial Infarction and Implanted Autologous Skeletal Stem Cell-Sheet
Utility of 13N-Ammonia Positron Emission Tomography to Visualize the Therapeutic Effect: A Case With Anteroseptal Myocardial Infarction and Implanted Autologous Skeletal Stem Cell-Sheet
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利用 13N-氨正电子发射断层扫描可视化治疗效果：前间壁心肌梗塞植入自体骨骼干细胞片一例
DOI：
10.1161/circimaging.122.014315
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Niinami Hiroshi
中科院分区：
文献类型：
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作者：
Yamamoto Atsushi;Nagao Michinobu;Ichihara Yuki;Niinami Hiroshi
一名68岁女性因广泛性房间隔心肌梗死引起心力衰竭多次住院，并被转介至我院进行心肌细胞片植入。已经采用了最佳药物治疗，并进行了心脏再同步化治疗。冠状动脉造影显示左侧冠状动脉前降支（LAD）近端无支架内再狭窄，左旋冠状动脉中部90%狭窄（LCX；分数血流储备：0.89），右侧冠状动脉远端75%狭窄（RCA；图1）。术前NH3-PET心肌灌注显像显示LAD内心肌梗死，但各区域无明显缺血。法援局的核磁共振；
A 68-year-old woman had been repeatedly hospitalized for heart failure caused by a broad anteroseptal myocardial infarction and was referred to our hospital for cardiomyocyte sheet implantation. Optimal medical therapy had already been introduced, and cardiac resynchronization therapy had been performed. Coronary artery angiography revealed a stent without in-stent restenosis in the proximal left anterior descending coronary artery (LAD), 90% stenosis in the middle left circumflex coronary artery (LCX; fractional flow reserve: 0.89), and 75% stenosis in the distal right coronary artery (RCA; Figure 1). Preoperative NH3-PET myocardial perfusion imaging showed myocardial infarction in the LAD but no significant ischemia in any territory. MFRs of the LAD,