MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn's disease
MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn's disease
复制标题
DOI：
10.1007/s00330-010-1976-3
复制
发表时间：
2011-04-01
影响因子：
5.9
通讯作者：
Gualdi, Gianfranco
中科院分区：
文献类型：
--
作者：
Casciani, Emanuele;Masselli, Gabriele;Gualdi, Gianfranco
这项前瞻性研究的目的是比较 MR 小肠造影 (MRE) 与小肠胶囊内窥镜 (SBCE) 对疑似克罗恩病 (CD) 儿科患者的诊断率。疑似 CD 儿科患者被认为有资格参加该研究。所有患者均接受了诊断检查，包括 1.5-T MRE、回肠结肠镜检查和食管胃十二指肠镜检查。如果 MRE 显示 SB 狭窄或肠外发现与症状一致，则不进行 SBCE。 60 名连续儿童患者（36 名男性；平均年龄 14 岁）被纳入该研究。 19 名患者的 CD 诊断呈阳性，29 名患者结果呈阴性，12 名患者患有其他胃肠道疾病。 37 名患者（61.7%）进行了 SBCE； 23 名患者被排除（5 名患者有狭窄，11 名患者有肠外发现，7 名患者父母拒绝）。 MRE和SBCE的准确性、敏感性和特异性分别为98.3%、100%、97.6%和91.9%、90.9%、92.3%。MRE和SBCE都是诊断疑似CD患者的准确方法。 MRE 可用作疑似 CD 的主要成像技术，因为它允许进入回肠狭窄，这构成 SBCE 的禁忌症并提供肠外信息。
The aim of this prospective study was to compare the diagnostic yield of MR enterography (MRE) with small-bowel capsule endoscopy (SBCE) in paediatric patients with suspected Crohn's disease (CD).Paediatric patients with suspected CD were considered eligible to be enrolled in the study. All patients underwent diagnostic work-up including 1.5-T MRE, ileo-colonoscopy and oesophagogastroduodenoscopy. SBCE was not performed if MRE showed SB stricture or extra-intestinal findings consistent with symptoms.Sixty consecutive paediatric patients (36 male; average age 14) were enrolled into the study. A positive diagnosis for CD was made in 19 patients, 29 had a negative result and 12 were affected by other gastro-intestinal conditions. SBCE was performed in 37 patients (61.7%); 23 patients were excluded (strictures in five, extra-intestinal findings in 11 and parents' refusal in seven cases). The accuracy, sensitivity, and specificity of MRE and SBCE were 98.3%, 100%, 97.6%, and 91.9%, 90.9%, 92.3%, respectively.Both MRE and SBCE are accurate methods for patients with suspected CD. MRE can be used as a primary imaging technique in suspected CD, in that it allows access to the ileal stricture, which forms a contra-indication for SBCE and provides extra-intestinal information.