Stereotactic surgery for subthalamic nucleus stimulation under general anesthesia: A retrospective evaluation of Japanese patients with Parkinson's disease
Stereotactic surgery for subthalamic nucleus stimulation under general anesthesia: A retrospective evaluation of Japanese patients with Parkinson's disease
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DOI：
10.1016/j.parkreldis.2006.07.008
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发表时间：
2007-01-01
影响因子：
4.1
通讯作者：
Kaji, Ryuji
中科院分区：
文献类型：
--
作者：
Yamada, Kazumchi;Goto, Satoshi;Kaji, Ryuji
我们回顾性比较了15例帕金森病患者在全身麻醉（GA）下接受双侧丘脑底核（STN）刺激的结果，其中10例患者在局部麻醉（LA）下接受刺激。术后3个月，两组中所有主要帕金森运动症状（采用统一帕金森病评定量表评估）均较术前基线显著改善。除了停药后的运动迟缓外，GA给药对术后运动和日常活动评分的改善没有不良影响。我们的研究结果表明，GA相比，有利的外科手术中的LA的双边小脑刺激。(c)2006爱思唯尔有限公司保留所有权利。
We compared retrospectively the outcome of bilateral subthalamic nucleus (STN) stimulation in 15 patients with Parkinson's disease who underwent the procedure under general anesthesia (GA) with that achieved in 10 patients under local anesthesia (LA). At 3 months postoperatively, all cardinal parkinsonian motor symptoms, evaluated on Unified Parkinson's Disease Rating Scale were significantly improved compared to preoperative baselines in both groups. The administration of GA did not adversely affect postoperative improvements in motor and daily activity scores, except for off-medication bradykinesia. Our results suggest that GA compares favorably with LA in surgical procedure for bilateral STN stimulation. (c) 2006 Elsevier Ltd. All rights reserved.