Heritability of poor language achievement among twins.
Heritability of poor language achievement among twins.
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双胞胎中语言成绩较差的遗传力。
DOI：
10.1044/jslhr.4101.188
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Buckwalter,PR
中科院分区：
文献类型：
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作者：
Tomblin,JB;Buckwalter,PR
为了考察与语言成绩差的家族关系的基础，研究人员研究了62对双胞胎和3组三胞胎，其中至少有一名成员在没有其他发育或感觉障碍的情况下表现出较差的口头语言状态。比较了单合子(MZ)和双合子(DZ)对语言不良的符合率。MZ对的一致性为0.96，而DZ对的一致性为0.69。采用DeFries-Fulker方法计算极端分数的遗传力，得到h2gof.45。对于那些只包含表现智商高于85的儿童，但至少有一名成员的语言低于-1SD的儿童对，也得到了类似的结果。对DZ双胞胎和至少有一个患病成员且年龄相似的单胞胎兄弟姐妹进行的比较表明，DZ双胞胎在语言成就方面比单胞胎更相似。因此，双胞胎似乎影响了那些至少有一名成员语言成绩较差的人的双胞胎相似性。这些结果支持了这样一种假设，即遗传因素导致没有其他发育或感觉障碍的儿童语言成绩差的可能性。
In order to examine the basis of familial associations with poor language achievement, 62 twinship pairs and 3 sets of triplets were studied in which at least one member presented poor oral language status in the absence of other developmental or sensory impairments. Rates of concordance for poor language were compared between the monozygotic (MZ) and dizygotic (DZ) pairs. Concordance for the MZ pairs was .96, whereas it was .69 for the DZ pairs. The DeFries-Fulker method for computing heritability of extreme scores was employed yielding a h2gof .45. Similar results were obtained for those pairs containing only children with performance IQs above 85, but with at least one member having language below –1SD. A comparison of DZ twins with singleton sibling pairs with at least one affected member and of similar age showed that DZ twins were more similar with respect to language achievement than singleton pairs. Thus, twinning appeared to have influenced twin resemblance among those where at least one member presented poor language achievement. These results support the hypothesis that genetic factors contribute to the liability of poor language achievement in children who do not present other developmental or sensory disorders.