C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men
C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men
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DOI：
10.1152/ajpregu.90936.2008
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发表时间：
2009-04-01
影响因子：
2.8
通讯作者：
Fernhall, Bo
中科院分区：
文献类型：
--
作者：
Heffernan, Kevin S.;Jae, Sae Young;Fernhall, Bo
Heffernan KS, Jae SY, Vieira VJ, Iwamoto GA, Wilund KR, Woods JA, Fernhall B.抗阻运动训练后c反应蛋白与心脏迷走神经活动的关系。[J] .中国生物医学工程学报，2016,31(6):888 - 888。2009年2月4日首次发表；doi: 10.1152 / ajpregu.90936.2008。与美国白人相比，非裔美国人有更高的高血压和糖尿病患病率，并且自主神经失调和炎症都与这些疾病状态的病因有关。本研究的目的是检查年轻非裔美国人和白人男性抗阻训练后心脏自主神经和全身炎症反应。采用线性（时域和频域）和非线性（样本熵）心率变异性、压力反射敏感性、强直和反射迷走神经活动以及运动后心率恢复来评估心脏迷走神经调节。c反应蛋白（CRP）和白细胞计数作为炎症标志物。22名白人和19名非裔美国男性完成了6周的阻力训练，随后进行了4周的运动去训练（Post 2）。阻力训练后，白人和非裔美国男性的样本熵、紧张性和反射性迷走神经活动以及心率恢复均有所增加（P < 0.05）。在去训练（Post 2）后，白人男性的样本熵、强直和反射迷走神经活动以及心率恢复恢复到基线值，但非裔美国男性仍高于基线值。虽然白人男性的白细胞计数或CRP没有变化，但这些炎症标志物在抗阻训练后在非裔美国男性中下降，在训练结束后仍保持下降（P < 0.05）。总之，抗阻训练改善了非裔美国男性的心脏自主神经功能，减少了炎症，这些适应性在训练结束后仍然存在。抗阻训练可能是改善年轻非裔美国男性心脏自主神经健康和减少炎症的重要生活方式改变。
Heffernan KS, Jae SY, Vieira VJ, Iwamoto GA, Wilund KR, Woods JA, Fernhall B. C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men. Am J Physiol Regul Integr Comp Physiol 296: R1098-R1105, 2009. First published February 4, 2009; doi: 10.1152/ajpregu.90936.2008.-African Americans have a greater prevalence of hypertension and diabetes compared with white Americans, and both autonomic dysregulation and inflammation have been implicated in the etiology of these disease states. The purpose of this study was to examine the cardiac autonomic and systemic inflammatory response to resistance training in young African-American and white men. Linear (time and frequency domain) and nonlinear (sample entropy) heart rate variability, baroreflex sensitivity, tonic and reflex vagal activity, and postexercise heart rate recovery were used to assess cardiac vagal modulation. C-reactive protein (CRP) and white blood cell count were used as inflammatory markers. Twenty two white and 19 African-American men completed 6 wk of resistance training followed by 4 wk of exercise detraining (Post 2). Sample entropy, tonic and reflex vagal activity, and heart rate recovery were increased in white and African-American men following resistance training (P < 0.05). Following detraining (Post 2), sample entropy, tonic and reflex vagal activity, and heart rate recovery returned to baseline values in white men but remained above baseline in African-American men. While there were no changes in white blood cell count or CRP in white men, these inflammatory markers decreased in African-American men following resistance training, with reductions being maintained following detraining (P < 0.05). In conclusion, resistance training improves cardiac autonomic function and reduces inflammation in African-American men, and these adaptations remained after the cessation of training. Resistance training may be an important lifestyle modification for improving cardiac autonomic health and reducing inflammation in young African-American men.