The search for correlates of age-related cochlear synaptopathy: Measures of temporal envelope processing and spatial release from speech-on-speech masking.
The search for correlates of age-related cochlear synaptopathy: Measures of temporal envelope processing and spatial release from speech-on-speech masking.
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DOI：
10.1016/j.heares.2021.108333
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发表时间：
2021-09-15
期刊：
影响因子：
2.8
通讯作者：
Wojtczak M
中科院分区：
文献类型：
--
作者：
Patro C;Kreft HA;Wojtczak M
老年人在不利的听力条件下往往难以理解言语。有人认为，听力正常或接近正常的听众，这些困难可能，至少部分是由于年龄相关的耳蜗突触病。本研究的目的是评估依赖于时间包络处理的听觉任务的性能是否显示与耳蜗突触病预期一致的年龄相关的缺陷。年龄在20至66岁的听众进行了测试，使用一系列的心理物理，电生理和言语感知的措施，刺激配置，促进编码的中，低自发率的神经纤维。获得执行功能的认知测量以控制与年龄相关的认知下降。不同测试的结果没有显着相关性，尽管假定依赖于共同的机制参与时间包络处理。只有间隙检测阈值的音调在噪音和空间释放的语音对语音掩蔽显着相关的年龄。年龄增长与认知执行功能受损有关。多变量回归分析表明，个体差异的听力灵敏度，听力测试的措施，和分数从非听觉认知测试没有显着贡献的空间释放的变异性，从语音语音掩蔽小目标/掩蔽空间分离，而年龄是一个显着的贡献者。
Older adults often experience difficulties understanding speech in adverse listening conditions. It has been suggested that for listeners with normal and near-normal audiograms, these difficulties may, at least in part, arise from age-related cochlear synaptopathy. The aim of this study was to assess if performance on auditory tasks relying on temporal envelope processing reveal age-related deficits consistent with those expected from cochlear synaptopathy. Listeners aged 20 to 66 years were tested using a series of psychophysical, electrophysiological, and speech-perception measures using stimulus configurations that promote coding by medium- and low-spontaneous-rate auditory-nerve fibers. Cognitive measures of executive function were obtained to control for age-related cognitive decline. Results from the different tests were not significantly correlated with each other despite a presumed reliance on common mechanisms involved in temporal envelope processing. Only gap-detection thresholds for a tone in noise and spatial release from speech-on-speech masking were significantly correlated with age. Increasing age was related to impaired cognitive executive function. Multivariate regression analyses showed that individual differences in hearing sensitivity, envelope-based measures, and scores from nonauditory cognitive tests did not significantly contribute to the variability in spatial release from speech-on-speech masking for small target/masker spatial separation, while age was a significant contributor.
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影响因子：
3
作者：
Bharadwaj HM;Verhulst S;Shaheen L;Liberman MC;Shinn-Cunningham BG
通讯作者：
Shinn-Cunningham BG
影响因子：
16.2
作者：
Chambers AR;Resnik J;Yuan Y;Whitton JP;Edge AS;Liberman MC;Polley DB
通讯作者：
Polley DB
DOI：
10.1523/jneurosci.2176-12.2012
发表时间：
2012-10-10
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Anderson S;Parbery-Clark A;White-Schwoch T;Kraus N
通讯作者：
Kraus N
DOI：
10.1044/jshr.3503.642
发表时间：
1992-06-01
期刊：
JOURNAL OF SPEECH AND HEARING RESEARCH
影响因子：
--
作者：
BACON, SP;GLEITMAN, RM
通讯作者：
GLEITMAN, RM
影响因子：
2.4
作者：
Dau, T;Kollmeier, B;Kohlrausch, A
通讯作者：
Kohlrausch, A