Profile of Immunoglobulin G and IgM Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Profile of Immunoglobulin G and IgM Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
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DOI:
10.1093/cid/ciaa489
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发表时间:
2020-10-15
影响因子:
11.8
通讯作者:
Liu, Lei
Liu, Lei
中科院分区:
医学1区
文献类型:
--
作者:
Qu, Jiuxin;Wu, Chi;Liu, Lei

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我们描述了严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)、核衣壳(N)蛋白和刺突(S)糖蛋白的血清学反应。大多数患者在发病后17至23天内出现了强劲的抗体反应。在危重患者中观察到延迟的,但更强烈的抗体反应。
We profiled the serological responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein and spike (S) glycoprotein. The majority of the patients developed robust antibody responses between 17 and 23 days after illness onset. Delayed, but stronger, antibody responses were observed in critical patients.