REVIEW OF THE MACROPHAGE DISAPPEARANCE REACTION
REVIEW OF THE MACROPHAGE DISAPPEARANCE REACTION
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DOI：
10.1002/jlb.57.3.361
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发表时间：
1995-03-01
影响因子：
5.5
通讯作者：
MORAHAN, PS
中科院分区：
文献类型：
--
作者：
BARTH, MW;HENDRZAK, JA;MORAHAN, PS
巨噬细胞（M phi s）在腹膜腔室中响应于某些刺激而经历称为巨噬细胞消失反应（MDR）的生理反应。本文就引起MDR的刺激因素、MDR与宿主免疫反应的关系以及MDR在M phi活化中的可能作用作一综述。这些数据表明，MDR发生在急性非特异性炎症和特异性免疫迟发型超敏反应过程中，MDR可能在M phi活化中起重要作用。
Macrophages (M phi s) undergo a physiological response known as the macrophage disappearance reaction (MDR) in response to certain stimuli in the peritoneal compartment. The types of stimuli that can cause the MDR, the relationship of the MDR to the host immunological response, and the possible role of the MDR in M phi activation are reviewed. The data indicate that the MDR occurs in response to both acute nonspecific inflammatory and specific immune delayed hypersensitivity processes and that the MDR may play an important role in M phi activation.