Roles of DNA Repair Proteins in Telomere Maintenance
Roles of DNA Repair Proteins in Telomere Maintenance
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DOI：
10.1271/bbb.90682
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发表时间：
2010-01
期刊：
影响因子：
--
通讯作者：
M. Ueno
中科院分区：
文献类型：
--
作者：
M. Ueno
端粒受到端粒特异性蛋白的保护和维持。此外，参与DNA修复的蛋白质，如Mre11-Rad50-Nbs1复合体、RPA和RecQ解旋酶，也参与端粒维持。本文将对这些蛋白在端粒维持中的作用及其与端粒特异性蛋白的功能关系进行综述。
Telomeres are protected and maintained by telomere-specific proteins. In addition, proteins involved in DNA repair, such as Mre11-Rad50-Nbs1 complex, RPA, and RecQ helicase, are also involved in telomere maintenance. In this review, the roles of these proteins in telomere maintenance and their functional relationships to the telomere-specific proteins will be discussed.