Bioinorganic chemistry.

Bioinorganic chemistry.
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生物无机化学。

DOI:
10.1039/c2dt90214a
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发表时间:
2013
期刊:
2003)
影响因子:
--
通讯作者:
Raven E
Raven E
中科院分区:
--
文献类型:
--
作者:
Raven E

文献摘要

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《道尔顿学报》生物无机化学特刊的想法最初是由杰米·汉弗莱(道尔顿学报的编辑)在至少四年前向我们中的一位(ER)提出的。其动机是试图在一期杂志中收录足够广泛的文章,以展示该学科的多样性,并强调光谱学、晶体学、分子生物学和酶学等现代方法如何应用于生物学中的金属离子研究。最重要的是,我们想强调无机化学在生物学中的持续贡献和重要性。无论是作为该领域的铁杆粉丝,还是作为更随意的读者,抑或是作为第一次希望深入研究该主题的人,在浏览这期杂志时,都值得停下来思考一下,并记住这门学科在相对较短时期内的演变。就在大约50年前,金属离子在生物学中起作用的观点只吸引了一小部分福音派信徒。从那时起,随着大量证据的积累,无机金属离子在生物学中扮演的角色的多样性得到了明确的证明,半信者和完全不信者都消失在了背景中。只要浏览一下《生物无机化学》的早期文本,就会发现这个领域在25年前几乎面目全非。已故的鲍勃•海(Bob Hay) 1987年出版的这本袖珍但内容全面的指南——最早出版的书之一——在200多页的篇幅里,不知怎么地总结了整个学科。今天要做同样的事情需要付出巨大的努力,我们没有尝试。相反,在过去一年左右的时间里,我和我的共同编辑(尼克·勒布伦、乔恩·麦克马斯特、简·雷迪克和奈杰尔·罗宾逊)一直在共同努力,制作一本颂扬这两者的杂志
The idea of a special issue in Bioinorganic Chemistry for Dalton Transactions was originally suggested to one of us (ER) by Jamie Humphrey (Editor of Dalton Transactions) at least four years ago. The motivation was to try to capture, in a single issue, a collection of articles that were broad enough to showcase the diversity of the discipline, and to highlight how modern methods of spectroscopy, crystallography, molecular biology and enzymology can be applied to the study of metal ions in biology. We wanted, most of all, to highlight the continuing contribution and importance of inorganic chemistry in biology. In browsing the issue–be that as a die-hard aficionado of the area, as a more casual reader, or indeed as someone wishing to delve for the first time into the subject–it is worth taking pause for thought and remembering the evolution of the discipline over a relatively short period. Even as little as perhaps 50 years ago the idea that metal ions had any role in biology appealed only to a small minority of evangelist believers. Since then, the semi-believers and the outright unbelievers have disappeared into the background as an overwhelming body of evidence has accumulated in the foreground to categorically demonstrate the diversity of roles that inorganic metal ions play in biology. One only has to glance at early texts in Bioinorganic Chemistry to see that the field as it was as little as 25 years ago is almost unrecognizable today. The late Bob Hay’s pocket-sized but fully comprehensive guide from 1987–one of the first books to appear1–somehow manages in its 200-odd pages to summarise the entire discipline. To do the same today would have required a truly herculean effort, and we did not attempt it. Instead, over the past year or so, my co-editors (Nick Le Brun, Jon McMaster, Jan Reedijk and Nigel Robinson) and I have been working together to produce an issue that celebrates both