Developmental trajectories of criteria of nicotine dependence in adolescence
Developmental trajectories of criteria of nicotine dependence in adolescence
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DOI：
10.1016/j.drugalcdep.2008.04.017
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发表时间：
2008-11-01
影响因子：
4.2
通讯作者：
Kandel, Denise B.
中科院分区：
文献类型：
--
作者：
Hu, Mei-Chen;Muthen, Bengt;Kandel, Denise B.
我们描述的性质和发展轨迹的DSM-IV尼古丁依赖的症状在青少年开始吸烟后的预测。数据来自芝加哥公立学校6-10年级的324名新吸烟者的纵向队列。每隔6个月面谈5次。DSM-IV尼古丁依赖症状的每月数据可持续36个月。生长混合模型应用于每月的历史，以确定尼古丁依赖的DSM-IV标准的轨迹。四类解决方案最适合数据：无DSM标准（47.7%）：早发/慢性病程（19.8%）：早发/缓解（17.3%）：晚发（15.2%）。在吸烟前钝性使用与三种症状轨迹相关。品行障碍和既往重度吸烟与2级（慢性）相关。行为障碍2级前4级（迟发性）。而对第一次烟草体验的愉快的初始敏感性与2级和3级（缓解）以及分化的2级前4级相关。新奇追求的特点类3。在早期出现症状的患者中，父母依赖性区分了慢性（2类）和缓解（3类）。作为西班牙裔减少了3级和4级的成员。三班的男生这些数据突出了父母尼古丁依赖作为后代早期和持续尼古丁依赖的风险因素的重要性。愉快的初始敏感性和早期依赖性发作的行为障碍。以及在吸烟之前对所有轨迹进行钝性使用。对依赖性开始的重要因素不一定与持续过程的因素相同。(C)2008爱思唯尔爱尔兰有限公司保留所有权利。
We describe the nature and predictors of developmental trajectories of symptoms of DSM-IV nicotine dependence in adolescence following smoking initiation. Data are front a longitudinal cohort of 324 new smokers from grades 6-10 in the Chicago Public Schools. interviewed 5 times at 6-month intervals. Monthly data on DSM-IV symptoms of nicotine dependence were available for 36 months. Growth Mixture modeling was applied to the monthly histories to identify trajectories of DSM-IV criteria of nicotine dependence. A four-class Solution best fitted the data: no DSM criterion (47.7%): early onset/chronic course (19.8%): early onset/remission (17.3%): late onset (15.2%). Blunt use prior to cigarette use was associated with the three symptomatic trajectories. Conduct disorder and prior heavy smoking were associated with Class 2 (chronic). Conduct disorder differentiated Class 2 front Class 4 (late onset). while pleasant initial sensitivity to the first tobacco experience was associated with Classes 2 and 3 (remit) and differentiated Class 2 front Class 4. Novelty seeking characterized Class 3. Parental dependence differentiated chronicity (Class 2) front remission (Class 3) among those who developed symptoms early. Being Hispanic reduced membership in Classes 3 and 4. and being male for Class 3. The data highlight the importance of parental nicotine dependence as a risk factor for early and sustained nicotine dependence by the offspring. pleasant initial sensitivity and Conduct disorder for early onset of dependence. and blunt use prior to smoking for all trajectories. The factors important for onset of dependence are not necessarily the same as those for Sustained Course. (C) 2008 Elsevier Ireland Ltd. All rights reserved.