Differential effects on cognitive functioning in 13-to 16-year-olds prenatally exposed to cigarettes and marihuana
Differential effects on cognitive functioning in 13-to 16-year-olds prenatally exposed to cigarettes and marihuana
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DOI：
10.1016/s0892-0362(03)00029-1
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发表时间：
2003-07-01
影响因子：
2.9
通讯作者：
Gray, R
中科院分区：
文献类型：
--
作者：
Fried, PA;Watkinson, B;Gray, R
对 145 名 13 至 16 岁青少年的认知表现进行了检查，已确定这些青少年在产前接触过大麻和香烟。受试者来自低风险、主要是中产阶级样本，参与一项正在进行的纵向研究。评估包括一般智力、成就、记忆力和执行功能（EF）方面的测试。与早期获得的结果一致，产前母亲吸烟与认知变量之间的最强关系与整体智力和听觉功能方面有关，而产前接触大麻与需要视觉记忆、分析和整合的任务呈负相关。根据与子宫内接触香烟和大麻相关的差异观察以及与这两种药物相关的认知变量的性质，讨论了结果的解释。 (C) 2003 Elsevier Science Inc. 保留所有权利。
Cognitive performance was examined in 145 thirteen- to sixteen-year-old adolescents for whom prenatal exposure to marihuana and cigarettes had been ascertained. The subjects were from a low-risk, predominantly middle-class sample participating in an ongoing, longitudinal study. The assessment battery included tests of general intelligence, achievement, memory, and aspects of executive functioning (EF). Consistent with results obtained at earlier ages, the strongest relationship between prenatal maternal cigarette smoking and cognitive variables was seen with overall intelligence and aspects of auditory functioning whereas prenatal exposure to marihuana was negatively associated with tasks that required visual memory, analysis, and integration. The interpretation of the results is discussed in terms of the differential observations related to in utero exposure to cigarettes and marihuana and the nature of the cognitive variables associated with the two drugs. (C) 2003 Elsevier Science Inc. All rights reserved.