FROZEN MUSCULOSKELETAL ALLOGRAFTS - A STUDY OF THE CLINICAL INCIDENCE AND CAUSES OF INFECTION ASSOCIATED WITH THEIR USE
FROZEN MUSCULOSKELETAL ALLOGRAFTS - A STUDY OF THE CLINICAL INCIDENCE AND CAUSES OF INFECTION ASSOCIATED WITH THEIR USE
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DOI：
10.2106/00004623-199072080-00003
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发表时间：
1990-09-01
影响因子：
5.3
通讯作者：
FERRARO, MJ
中科院分区：
文献类型：
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作者：
TOMFORD, WW;THONGPHASUK, J;FERRARO, MJ
对冷冻同种异体肌肉骨骼移植物的临床发生率和感染原因进行了回顾性研究。对本院骨库提供的324块异体骨片的研究结果表明，股骨头及其他同种异体小骨和软组织移植的患者临床感染发生率可忽略不计。在接受骨肿瘤治疗的患者中，与使用骨关节或骨干移植物等大型同种异体移植物有关的感染发生率约为5%，在接受髋关节置换翻修术的患者中，感染发生率约为4%。这些感染率与使用大型同种异体移植物或无菌假体装置的类似系列报告的感染率没有实质性差异。感染的原因很难确定，但异体移植物的污染可能不是大多数患者的一个因素。
A retrospective study was performed to determine the clinical incidence and causes of infection related to the use of frozen musculoskeletal allografts. The results of this study of 324 grafts, prepared and supplied by our hospital bone bank, showed that the patients in whom femoral head grafts and other small bone and soft-tissue allografts were used had a negligible clinical incidence of infection. The incidence of infection related to the use of large allografts, such as osteoarticular or diaphyseal grafts, was approximately 5 per cent in patients who had treatment for a bone tumor and 4 per cent in those who had revision of a hip arthroplasty. These rates of infection were not substantially different from those that have been reported in similar series in which large allografts or sterilized prosthetic devices were used. The causes of the infections were difficult to determine, but contamination of the allograft was probably not a factor in most patients.