Reliability testing of the quantitative myasthenia gravis score

Reliability testing of the quantitative myasthenia gravis score
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DOI:
10.1111/j.1749-6632.1998.tb11015.x
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发表时间:
1998-01-01
期刊:
MYASTHENIA GRAVIS AND RELATED DISEASES
影响因子:
--
通讯作者:
Bryan, WW
Bryan, WW
中科院分区:
其他
文献类型:
--
作者:
Barohn, RJ;McIntire, D;Bryan, WW

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方法采用0 ~ 3分量表(总分0-39分)测量13项客观指标。9名受试者,5名MG和4名正常人,由7名临床评价者(CE)独立检查。五名CE检查了五个科目,三名CE检查了四个科目。所有MG患者血清AChR-Ab滴度均为阳性。QMG的可靠性估计为使用方差分析的合并标准差估计值。
METHODSThirteen objective parameters were measured on a 0 to 3 point scale (total score range 0–39). Nine subjects, five with MG and four normals, were independently examined by seven clinical evaluators (CEs). Five CEs examined five subjects and three CEs examined four subjects. All MG patients had positive serum AChR-Ab titers. The reliability of the QMG was estimated as the pooled standard deviation estimate using an analysis of variance.RESULTS