Odontogenic tumors: A study of 1309 cases in a Chinese population

Odontogenic tumors: A study of 1309 cases in a Chinese population
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牙源性肿瘤:对中国人群 1309 例病例的研究。

DOI:
10.1016/j.oraloncology.2008.11.001
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发表时间:
2009-08-01
期刊:
影响因子:
4.8
通讯作者:
Li, Tie-Jun
Li, Tie-Jun
中科院分区:
医学2区
文献类型:
--
作者:
Luo, Hai-Yan;Li, Tie-Jun

文献摘要

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为了确定牙源性肿瘤(OTs)在中国人群中的相对频率,对1985-2006年期间北京大学口腔医学院和口腔医院口腔病理科的所有OTs文件进行了系统回顾。每个病例的诊断均根据2005年发布的WHO OT组织学分类进行确认。对这些骨肉瘤的相关临床病理资料进行分析,并与以前的系列进行比较。本系列约占同期我科所有病理标本的3.92%。良性占94.04%,恶性占5.06%。良性肿瘤以角化囊性牙源性肿瘤最多见(38.73%),其次为成釉细胞瘤(36.52%)和牙源性肿瘤(6.11%)。其余肿瘤的患病率似乎是罕见的。总之,牙源性肿瘤在中国人群中是不常见的。本研究确定了我们的数据和以前的研究从非洲和亚洲之间的一些相似之处和一些差异相比,从美国和欧洲国家的报告。(C)2008爱思唯尔有限公司保留所有权利。
To determine the relative frequency of odontogenic tumors (OTs) in a Chinese population, files from the department of oral pathology, Peking University School and Hospital of Stomatology, were systematically reviewed for all OTs during the period 1985-2006. Diagnosis of each case was confirmed according to the WHO histological classification for OTs published in 2005. The relevant clinicopathological data of these OTs were analyzed and compared with those of previous series. The present series represents approximately 3.92% of all pathologic specimens accessioned in our department over the same period of time. Of the 1309 OTs, 94.04% were benign and 5.06% were malignant. The most frequent benign tumor was keratocystic odontogenic tumor (38.73%), followed by ameloblastoma (36.52%) and odontomas (6.11%). The prevalence of the remaining tumors appears to be rare. In conclusion, odontogenic tumors are in general uncommon lesions in this Chinese population. The present study identifies some similarities between our data and the previous studies from Africa and Asia and some differences in comparison to the reports from American and European countries. (C) 2008 Elsevier Ltd. All rights reserved.