Why Do People Living with HIV Adhere to Antiretroviral Therapy and Not Comorbid Cardiovascular Disease Medications? A Qualitative Inquiry
Why Do People Living with HIV Adhere to Antiretroviral Therapy and Not Comorbid Cardiovascular Disease Medications? A Qualitative Inquiry
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DOI：
10.2147/ppa.s254882
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发表时间：
2020-01-01
影响因子：
2.2
通讯作者：
Bosworth, Hayden B.
中科院分区：
文献类型：
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作者：
Muiruri, Charles;Sico, Isabelle P.;Bosworth, Hayden B.
背景：在实现病毒抑制后，艾滋病毒感染者（PLWH）必须重点预防心血管疾病（CVD）等非艾滋病合并症，以提高他们的生活质量和寿命。尽管与未感染 HIV 的个体相比，PLWH 患 CVD 的风险较高，但 PLWH 通常达不到 CVD 预防的循证治疗目标；人们对感染者不符合指南建议的原因知之甚少。本研究的目的是确定与已实现病毒抑制的感染者坚持使用 CVD 药物相关的因素。方法：定性数据来自形成性研究，旨在为美国三个大型学术医疗中心的护士主导的干预试验的调整以改善心血管健康提供信息。使用基于扎根理论的原则指导的内容分析对转录本进行分析。结果：51 人实现了病毒抑制（
Background: After achieving viral suppression, it is critical for persons living with HIV (PLWH) to focus on prevention of non-AIDS comorbidities such as cardiovascular disease (CVD) in order to enhance their quality of life and longevity of life. Despite PLWH elevated risk of developing CVD compared to individuals without HIV, PLWH do not often meet evidence-based treatment goals for CVD prevention; the reasons for PLWH not meeting guideline recommendations are poorly understood. The objective of this study was to identify the factors associated with adherence to CVD medications for PLWH who have achieved viral suppression.Methods: Qualitative data were obtained from formative research conducted to inform the adaptation of a nurse-led intervention trial to improve cardiovascular health at three large academic medical centers in the United States. Transcripts were analyzed using content analysis guided by principles drawn from grounded theory.Results: Fifty-one individuals who had achieved viral suppression (