Optical coherence tomography of the larynx in the awake patient
Optical coherence tomography of the larynx in the awake patient
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DOI：
10.1016/j.otohns.2007.12.005
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发表时间：
2008-04-01
影响因子：
3.4
通讯作者：
Wong, Brian J. F.
中科院分区：
文献类型：
--
作者：
Sepehr, Ali;Armstrong, William B.;Wong, Brian J. F.
d目标：为了证明一种新的灵活的光纤传输system.Study设计：前瞻性的临床试验。主题和方法：成像进行了17个清醒的病人在清醒的病人进行光学相干断层扫描的人喉的可行性。一个灵活的光学相干断层扫描探头插入通过鼻子，并放置在附近或轻轻接触喉组织下直接内镜visualization.Results：图像成功地获得了所有喉亚位点，并清楚地识别喉粘膜显微解剖。几个关键的探头设计修改提高了旋转和角度控制的远端，同时允许线性平移的探头，并允许更准确的附着到目标组织，这是至关重要的经鼻喉imaging.CONCLUSION：这项研究表明了清醒的经鼻喉光学相干断层扫描的可行性，并确定关键仪器需要获得有用的图像。C 2008年美国耳鼻咽喉头颈外科学会基金会。All rights reserved.
d OBJECTIVE: To demonstrate the feasibility of performing optical coherence tomography of the human larynx on the awake patient with a novel flexible fiberoptic delivery system.STUDY DESIGN: Prospective clinical trial.SUBJECTS AND METHODS: Imaging was performed in 17 awake patients. A flexible optical coherence tomography probe was inserted through the nose and placed in near or gentle contact with laryngeal tissues under direct endoscopic visualization.RESULTS: Images were successfully obtained from all laryngeal subsites and clearly identified laryngeal mucosal microanatomy. Several critical probe design modifications improved rotational and angular control of the distal tip while allowing linear translation of the probe and allowing more accurate apposition of the probe onto target tissues, which is critical for transnasal laryngeal imaging.CONCLUSION: This Study demonstrates the feasibility of awake transnasal laryngeal optical coherence tomography and identifies key instrumentation needed to obtain Useful images. C 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.