Selective betainization of 2-(dimethylamino)ethyl methacrylate residues in tertiary amine methacrylate diblock copolymers and their aqueous solution properties
Selective betainization of 2-(dimethylamino)ethyl methacrylate residues in tertiary amine methacrylate diblock copolymers and their aqueous solution properties
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DOI：
10.1016/j.polymer.2003.09.027
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发表时间：
2003-11-01
期刊：
影响因子：
4.6
通讯作者：
Bütün, V
中科院分区：
文献类型：
--
作者：
Bütün, V
以甲基丙烯酸二甲氨基乙酯（DMA）和甲基丙烯酸二乙氨基乙酯（DEA）、甲基丙烯酸二异丙氨基乙酯（DPA）、甲基丙烯酸吗啉基乙酯（MEMA）为单体，采用基团转移聚合（GTP）方法进行嵌段共聚。这些二嵌段共聚物中的每一个的DMA残基在温和条件下使用1，3-丙烷磺内酯选择性甜菜碱化，得到一系列新型甜菜碱二嵌段共聚物。这些选择性甜菜碱化的共聚物可以在室温下在没有共溶剂的情况下在水性介质中以分子形式溶解，其中胶束化在明智地调节溶液pH、温度或电解质浓度时可逆地发生。在所有三种情况下，形成稳定的嵌段共聚物胶束与甜菜碱化的DMA冠和流体动力学直径为10-46 nm。DMA残基的选择性甜菜碱化显著降低了叔胺甲基丙烯酸酯嵌段共聚物（DMA-DEA、DMA-DPA和DMA-MEMA）的表面活性并增加了溶解度。(C)2003 Elsevier Ltd.保留所有权利。
2-(dimethylamino)ethyl methacrylate (DMA) was block copolymerized in turn with three other tertiary amine methacrylate comonomers, namely 2-(diethylamino)ethyl methacrylate (DEA), 2-(diisopropylamino)ethyl methacrylate (DPA) and 2-(N-morpholino)ethyl methacrylate (MEMA), using group transfer polymerization (GTP). The DMA residues of each of these diblock copolymers were selectively betainized using 1,3-propane sultone under mild conditions to yield a series of novel betaine diblock copolymers. These selectively betainized copolymers could be dissolved molecularly without co-solvents in aqueous media at room temperature, with micellization occurring reversibly on judicious adjustment of the solution pH, temperature or electrolyte concentration. In all three cases, stable block copolymer micelles were formed with betainized-DMA coronas and hydrodynamic diameters of 10-46 nm. The selective betainization of the DMA residues dramatically reduces the surface activity and increase the solubility of the tertiary amine methacrylate block copolymers (DMA-DEA, DMA-DPA and DMA-MEMA). (C) 2003 Elsevier Ltd. All rights reserved.