Plasmid-Related Transmissibility and Multiple Drug Resistance in Streptococcus faecalis subsp. zymogenes Strain DS16
Plasmid-Related Transmissibility and Multiple Drug Resistance in Streptococcus faecalis subsp. zymogenes Strain DS16
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粪链球菌亚种的质粒相关传播性和多重耐药性。
DOI：
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发表时间：
1979
影响因子：
4.9
通讯作者：
D. Clewell
中科院分区：
文献类型：
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作者：
P. Tomich;F. An;S. Damle;D. Clewell
粪链球菌粪亚种发现产酶菌株DS 16含有两种质粒，命名为pAD 1（35兆道尔顿）和pAD 2（15兆道尔顿）。pAD 1是可传播的，决定溶血素-细菌素，而pAD 2是非接合性的，决定对红霉素、链霉素和卡那霉素的抗性。pAD 2可以被pAD 1动员，但通常涉及pAD 1-pAD 2共整合体的形成。
Streptococcus faecalis subsp. zymogenes strain DS16 was found to harbor two plasmids, designated pAD1 (35 megadaltons) and pAD2 (15 megadaltons). pAD1 is transmissible and determines a hemolysin-bacteriocin, whereas pAD2 is non-conjugative and determines resistance to erythromycin, streptomycin, and kanamycin. pAD2 could be mobilized by pAD1, but usually involved formation of a pAD1-pAD2 cointegrate.