Clinical aspects of ‘Q’ fever
Clinical aspects of ‘Q’ fever
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“Q”热的临床方面
DOI：
10.1136/pgmj.49.574.539
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发表时间：
1973
影响因子：
5.1
通讯作者：
G. L. Brown
中科院分区：
文献类型：
--
作者：
G. L. Brown
Q热是一种急性发热性疾病，主要见于农业社区成员。这种感染主要通过吸入受感染的灰尘从绵羊和奶牛感染，但也可以通过生奶传播。症状与流行性感冒有明显的相似之处，在大多数情况下，这种疾病会自动消失。确诊最好是通过证明补体结合抗体的升高。约三分之一的病例在X光片上可见肺部斑片状实变，偶尔感染会植入先前受损的心脏瓣膜，引起亚急性细菌性心内膜炎。可用四环素或甲氧苄啶磺胺甲恶唑治疗。
‘Q’ fever is an acute febrile illness seen mainly among members of the farming community. The infection is contracted from sheep and cows mainly by inhalation of infected dust, but can be spread by raw milk. The symptoms bear a marked resemblance to influenza and in the majority of cases the illness clears up spontaneously. A firm diagnosis can best be made by demonstrating a rise in complement fixing antibodies. Patchy consolidation of the lungs is seen on X-ray in about one-third of the cases and occasionally the infection becomes implanted on previously damaged heart valves and gives rise to subacute bacterial endocarditis. Treatment with tetracycline or trimethoprim sulphamethoxazole is indicated.