Interventions to improve recruitment and retention in clinical trials: a survey and workshop to assess current practice and future priorities.
Interventions to improve recruitment and retention in clinical trials: a survey and workshop to assess current practice and future priorities.
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改善临床试验中招聘和保留的干预措施：评估当前实践和未来优先事项的调查和研讨会。
DOI：
10.1186/1745-6215-15-399
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发表时间：
2014-10-16
期刊：
影响因子：
2.5
通讯作者：
Williamson P
中科院分区：
文献类型：
--
作者：
Bower P;Brueton V;Gamble C;Treweek S;Smith CT;Young B;Williamson P
尽管对基础设施进行了大量投资，但许多审判在征聘和留用人员方面仍然面临挑战。我们认为，没有足够的重点放在发展和测试的招聘和保留干预措施。在本文中，我们总结了现有的评论干预措施，以提高招聘和保留。我们报告了来自英国临床试验单位的调查数据，以表明这些单位用于鼓励招募和保留的干预措施的范围。我们在最近的一次研讨会上提出了与会者的意见，并提出了一份供评估的招聘干预措施的优先清单（由研讨会与会者投票决定）。我们还讨论了有关招聘干预措施的测试更广泛的问题。用于鼓励招募和保留的方法被分类为：患者接触，患者便利，对招募人员的支持，监测和系统，激励措施，设计，资源和人为因素。调查对象认为值得调查的干预措施分为三类：培训研究中心工作人员、与患者沟通和激励措施。大量资源继续投入临床试验和其他高质量研究，但招募仍然是一个重大挑战。需要采用创新方法来制定、测试和实施招聘干预措施。本文的在线版本（doi：10.1186/1745-6215-15-399）包含补充材料，可供授权用户使用。
Despite significant investment in infrastructure many trials continue to face challenges in recruitment and retention. We argue that insufficient focus has been placed on the development and testing of recruitment and retention interventions. In this current paper, we summarize existing reviews about interventions to improve recruitment and retention. We report survey data from Clinical Trials Units in the United Kingdom to indicate the range of interventions used by these units to encourage recruitment and retention. We present the views of participants in a recent workshop and a priority list of recruitment interventions for evaluation (determined by voting among workshop participants). We also discuss wider issues concerning the testing of recruitment interventions. Methods used to encourage recruitment and retention were categorized as: patient contact, patient convenience, support for recruiters, monitoring and systems, incentives, design, resources, and human factors. Interventions felt to merit investigation by respondents fell into three categories: training site staff, communication with patients, and incentives. Significant resources continue to be invested into clinical trials and other high quality studies, but recruitment remains a significant challenge. Adoption of innovative methods to develop, test, and implement recruitment interventions are required. The online version of this article (doi:10.1186/1745-6215-15-399) contains supplementary material, which is available to authorized users.
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影响因子：
2.5
作者：
Moynihan C;Lewis R;Hall E;Jones E;Birtle A;Huddart R;SPARE Trial Management Group
通讯作者：
SPARE Trial Management Group
影响因子：
8.4
作者：
Brueton, Valerie C;Tierney, Jayne;Stenning, Sally;Harding, Seeromanie;Meredith, Sarah;Nazareth, Irwin;Rait, Greta
通讯作者：
Rait, Greta
影响因子：
2.5
作者：
McDonald, Alison M.;Knight, Rosemary C.;Snowdon, Claire
通讯作者：
Snowdon, Claire
影响因子：
4
作者：
Nakash, Rachel A;Hutton, Jane L;Lamb, Sarah E
通讯作者：
Lamb, Sarah E
影响因子：
2.2
作者：
Graffy, Jonathan;Grant, Julie;Kinmonth, Ann Louise
通讯作者：
Kinmonth, Ann Louise