Techniques and applications of image correlation in radiotherapy treatment planning.
Techniques and applications of image correlation in radiotherapy treatment planning.
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图像相关技术及其在放射治疗计划中的应用。
DOI：
10.1159/000413236
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发表时间：
1987
影响因子：
--
通讯作者：
Chen,GT
中科院分区：
文献类型：
--
作者：
Kessler,ML;Pitluck,S;Chen,GT
需要准确地将一项成像研究中的感兴趣体积与另一项相关。举几个与放射治疗计划有关的例子：(A)MRI在确定中枢神经肿瘤和邻近关键大脑结构的相对位置方面非常有用。将肿瘤和关键器官的位置从MRI映射到CT以进行治疗计划对于精确的剂量计算是必要的；(B)术前扫描可以清楚地显示肿瘤。在肿瘤切除后，放射治疗师可能需要知道术前肿瘤位置的边界，同时在术后CT研究中确定靶点；(C)三维放射剂量分布可以与治疗前和治疗后的成像研究相关联，以了解治疗的效果、肿瘤复发或治疗相关并发症。由此，可通过剂量体积直方图分析收集和分析器官部分体积的剂量响应信息[1]。图像相关性的定量方法可以为许多临床问题提供解决方案。在关联不同的医学成像研究时，整合这些数据的负担主要落在医生身上。通常，多个成像研究的硬拷贝可以在灯箱上查看，结构可以用铅笔从一个研究转移到另一个研究。复杂因素包括：(A)患者的位置；(B)切片厚度或像素大小；(C)在不同模式下可见的解剖结构(例如：骨/空气界面在CT中清晰可见，但在MRI中不可见)；(D)空间分辨率；以及(E)成像模式的图像失真(MRI磁场
A need exists to accurately correlate volumes of interest in one imaging study with another. To cite a few examples relevant to radiation therapy planning:(a) MRI has been extremely useful in defining central nervous tumors and the relative location of adjacent critical brain structures. Mapping tumor and critical organ location from MRI to CT for treatment planning is necessary for accurate dose calculations;(b) a tumor may be visualized clearly on a preoperative scan. After resection, the radiation therapist may need to know the boundaries of the preoperative tumor location while defining the target on a postoperative CT study;(c) three-dimensional radiation dose distributions can be correlated with pre-and posttherapy imaging studies to understand the efficacy of therapy, tumor recurrence, or treatment-related complication. From this, dose response information for partial volumes of organs may be gathered and analyzed through dose volume histogram analysis [1]. A quantitative approach to image correlation can provide a solution for many of these clinical problems.In correlating different medical imaging studies, often performed in different planes by a different modality, the burden to integrate these data has fallen primarily on the physician. Typically, hardcopy of the multiple imaging studies are viewed on lightboxes, and structures are transferred from one study to another by pencil. Complicating factors include differ-ences in (a) patient position;(b) slice thickness or pixel size;(c) anatomy visible in the different modalities (example: bone/air interfaces are clearly seen in CT but not visible in MRI);(d) spatial resolution, and (e) image distortions characteristic of the imaging modality (MRI magnetic field