Mesodynamics: watching vesicle formation in situ by small-angle neutron scattering
Mesodynamics: watching vesicle formation in situ by small-angle neutron scattering
复制标题
介观动力学：通过小角度中子散射原位观察囊泡形成
DOI：
10.1007/s00396-010-2212-z
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发表时间：
2010
影响因子：
2.4
通讯作者：
M. Gradzielski
中科院分区：
文献类型：
--
作者：
Katharina Bressel;M. Muthig;S. Prévost;I. Grillo;M. Gradzielski
自聚集体系根据两亲物的类型和浓度形成多种不同的结构。形态变化可以通过混合两种表面活性剂溶液与停流技术和观察高度时间分辨SANS实验，从而允许获得的结构信息与25-50毫秒的时间分辨率。在这里，通过混合两性离子型十四烷基二甲基氧化胺（TDMAO）与阴离子型全氟辛烷磺酸锂（LiPFOS）的单层囊泡的形成作为混合比的函数进行了研究。SANS数据进行了分析的结构变化，特别是相对于中间结构。囊泡形成通过盘状胶束作为中间体发生，所述中间体在达到一定尺寸后接近形成非常单分散的单层囊泡。这一过程是由双层的弯曲能和盘边缘的线能之间的竞争控制的，其特征时间是由静电斥力控制的，静电斥力由TDMAO/LiPFOS的比例决定。
Self-aggregating systems form a large variety of different structures depending on type and concentration of the amphiphiles. Morphological changes can be triggered by mixing two surfactant solutions with the stopped-flow technique and observing by highly time-resolved SANS experiments, thereby allowing to obtain of structural information with 25–50 ms time resolution. Here, the formation of unilamellar vesicles by mixing zwitterionic tetradecyldimethylamine oxide (TDMAO) with the anionic lithium perfluorooctanesulfonate (LiPFOS) was studied as a function of the mixing ratio. SANS data were analyzed in terms of the structural changes and especially with respect to intermediate structures. Vesicle formation occurs via disk-like micelles as intermediates that close to form very monodisperse unilamellar vesicles after reaching a certain size. This process is controlled by the competition between bending energy of the bilayer and the line energy of the disk rim, and its characteristic time is controlled by the electrostatic repulsion that is determined by the TDMAO/LiPFOS ratio.
DOI：
10.1073/pnas.98.4.1353
发表时间：
2001-02
影响因子：
11.1
作者：
H. T. Jung;B. Coldren;J. Zasadzinski;D. J. Iampietro;E. Kaler
通讯作者：
H. T. Jung;B. Coldren;J. Zasadzinski;D. J. Iampietro;E. Kaler
影响因子：
3.9
作者：
Grillo, I.;Penfold, J.;Cousin, F.
通讯作者：
Cousin, F.