Preferential binding of imaginal disk cells to embryonic segments of Drosophila.
Preferential binding of imaginal disk cells to embryonic segments of Drosophila.
复制标题
成虫盘细胞优先结合果蝇胚胎片段。
作者：
Gauger,A;Fehon,RG;Schubiger,G
细胞识别和选择性粘附对于图案形成可能很重要；果蝇中的此类过程可能负责节段边界的维持、变态成虫盘的形态发生以及神经发生过程中轴突生长的路径。由于来自果蝇不同成虫盘的细胞能够相互识别和分类4,5，我们决定研究这些幼虫细胞是否能够识别并结合完整胚胎的表皮。我们在这里报告，成虫盘细胞优先结合到它们所衍生的胚胎节段的表皮：胸盘细胞结合到胸节，生殖盘细胞结合到腹节。此外，胸盘细胞无偏好地识别并结合同源突变体 Df(3R)P9 的所有片段（参考文献 6）。因此，我们得出结论，相同节段起源的细胞在不同的发育阶段具有相似的识别特性。
Cell recognition and selective adhesion may be important in pattern formation; such processes inDrosophila melanogastercould be responsible for the maintenance of segment boundaries1, the morphogenesis of metamorphosing imaginal disks2, and the paths of axon outgrowth during neurogenesis3. As cells from different imaginal disks ofDrosophilaare able to recognize and sort out from one another4,5, we decided to investigate whether these larval cells could recognize and bind to the epidermis of intact embryos. We report here that imaginal disk cells bind preferentially to the epidermis of the embryonic segments from which they are derived: thoracic disk cells to thoracic segments and genital disk cells to abdominal segments. Furthermore, thoracic disk cells recognize and bind, without preference, to all segments of the homoeotic mutantDf(3R)P9(ref. 6). We conclude, therefore, that cells of the same segmental origin have similar recognition properties at different developmental stages.