Use of EHRs data for clinical research: Historical progress and current applications
Use of EHRs data for clinical research: Historical progress and current applications
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DOI：
10.1002/lrh2.10076
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发表时间：
2019-01-01
影响因子：
3.1
通讯作者：
Kush, Rebecca Daniels
中科院分区：
文献类型：
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作者：
Nordo, Amy Harris;Levaux, Hugh P.;Kush, Rebecca Daniels
重复使用EHR数据进行临床研究的好处是多方面的。它们预示着有机会以更低的成本更快地为患者带来新的治疗方法，并通过更快的临床研究数据采集来加速学习健康周期。事实证明，可以节省时间，简化工作流程和流程，并显着提高数据质量。试点项目和现在用于监管提交的实际调查性试验表明，这些益处通过利用EHR进行研究来支持临床研究的转型。在最近一次专注于桥接临床研究和临床护理的合作会议上，小组成员就如何利用最新标准和技术促进从EHR系统到临床研究数据库的数据传输以及相关的数据质量改进提供了不同的观点。小组成员还讨论了在临床研究中利用EHR的其他途径。尽管有改进和令人兴奋的可能性，但仍有许多工作要做。数据所有权和访问权、关注元数据和结构化数据以促进数据共享，以及更广泛地采用全球标准，是开展合作的关键领域。随着世界各地采用EHR的稳步增长，这是所有利益相关者共同努力并创造环境的绝佳时机，以便EHR可以更容易地用于研究。因此，可以提高研究能力，以提供更多高质量的信息，这将有助于建立快速、持续学习的卫生系统，使所有患者都能从中受益。
The benefits of reusing EHR data for clinical research studies are numerous. They portend the opportunity to bring new therapies to patients sooner, potentially at a lower cost, and to accelerate learning health cycles-through faster data acquisition in clinical research studies. Metrics have proven that time can be saved, workflow and processes streamlined, and data quality increased significantly. Pilot projects and now actual investigational trials used for regulatory submissions have shown that these benefits support the transformation of clinical research by leveraging EHRs for research. Panelists at a recent collaborative focused on bridging clinical research and clinical care offered varying perspectives on how the latest standards and technologies could be leveraged to facilitate data transfer from EHR systems into clinical research databases, as well as the associated improvements in data quality. Panelists also discussed other avenues to leverage EHR in clinical research. Improvements and exciting possibilities notwithstanding, much work remains. Data ownership and access, attention to metadata and structured data for data sharing, and broader adoption of global standards are key areas for collaboration. With the steady increase in adoption of EHRs around the world, this is an excellent time for all stakeholders to work together and create an environment such that EHRs can be used more readily for research. The capacity for research can thus be increased to provide more high-quality information that will contribute to rapid continuous learning health systems from which all patients can benefit.