Similar neural mechanisms for perceptual guesses and free decisions
Similar neural mechanisms for perceptual guesses and free decisions
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DOI：
10.1016/j.neuroimage.2012.09.064
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发表时间：
2013-01-15
期刊：
影响因子：
5.7
通讯作者：
Haynes, John-Dylan
中科院分区：
文献类型：
--
作者：
Bode, Stefan;Bogler, Carsten;Haynes, John-Dylan
当我们在具有挑战性的条件下面对知觉选择时，我们可能会认为这纯粹是猜测。但是大脑的哪个区域决定了我们猜测的结果呢？一种可能性是，更高层次的大脑区域可能有助于打破相同选择之间的对称性。在这里，我们直接研究了知觉猜测是否与其他类型的自由决策共享大脑网络。我们训练了一个基于fMRI的模式分类器来区分两个感知猜测，并测试它是否能够预测类似的非感知选择的结果，就像在传统的自由选择任务中一样。内侧后顶叶皮层的激活模式与知觉猜测的自由决策交叉预测，反之亦然。这种可互换性有力地说明了这两种决策的神经代码相似。后顶叶皮层可能是一个一般领域系统的一部分，当没有选择的可能性或价值时，它可以帮助解决决策冲突，从而防止行为僵局。(C)2012 Elsevier Inc. All rights reserved.
When facing perceptual choices under challenging conditions we might believe to be purely guessing. But which brain regions determine the outcome of our guesses? One possibility is that higher-level, domain-general brain regions might help break the symmetry between equal-appearing choices. Here we directly investigated whether perceptual guesses share brain networks with other types of free decisions. We trained an fMRI-based pattern classifier to distinguish between two perceptual guesses and tested whether it was able to predict the outcome of similar non-perceptual choices, as in conventional free choice tasks. Activation patterns in the medial posterior parietal cortex cross-predicted free decisions from perceptual guesses and vice versa. This inter-changeability strongly speaks for a similar neural code for both types of decisions. The posterior parietal cortex might be part of a domain-general system that helps resolve decision conflicts when no choice option is more or less likely or valuable, thus preventing behavioural stalemate. (C) 2012 Elsevier Inc. All rights reserved.