Black-Blood Multicontrast Imaging of Carotid Arteries with DANTE-prepared 2D and 3D MR Imaging
Black-Blood Multicontrast Imaging of Carotid Arteries with DANTE-prepared 2D and 3D MR Imaging
复制标题
DOI：
10.1148/radiol.14131717
复制
发表时间：
2014-11-01
期刊：
影响因子：
19.7
通讯作者：
Jezzard, Peter
中科院分区：
文献类型：
--
作者：
Li, Linqing;Chai, Joshua T.;Jezzard, Peter
目的：前瞻性比较延迟交替张动定制激发（DANTE）制备模块与传统双反转恢复（DIR）和运动敏感驱动平衡（MSDE）制备模块的黑血（BB）成像效率，并引入一种新的三维（3D） t1加权磁共振（MR）成像序列。材料和方法：根据机构审查委员会批准的方案，对10名健康志愿者和15名患者进行颈动脉壁成像。二维（2D）涡轮自旋回波（TSE）和三维快速低角度拍摄（FLASH）序列作为读出模块。在颈动脉分叉区域获取dante制备的T1、T2和质子密度加权二维TSE图像，以及dante制备的T1加权三维FLASH（以下简称3D DASH）图像。为了比较，还获得了二维dir -制备、二维msde -制备的多对比度TSE和三维msde -制备的FLASH（以下简称3D MERGE） MR图像。计算了所有序列单位时间内的有效噪比（cnref）。采用配对t检验检验组内血管壁cnref的差异。结果：dante制备的T1-、T2-和质子密度加权序列的CNReff分别为27.3、14.7和25.7 mm(-1)min-(1/2)；与现有方法获得的CNReff相比，这代表了大约25%-100%的改善（P < 0.05）。3D DASH技术被证明是一种快速（每段< 2秒）和高空间分辨率（0.6 mm各向同性）的BB技术，比3D MERGE技术具有更高的信噪比效率（75%-100%的改进，P < 0.001）。结论：dante制备的多层对比二维BB技术是一种很有前途的颈动脉壁磁共振成像新工具。此外，3D DASH序列可实现颈动脉壁的3D高空间分辨率快速T1加权成像。(C) RSNA, 2014年
Purpose: To prospectively compare the black-blood (BB) imaging efficiency of a delay alternating with nutation for tailored excitation (DANTE) preparation module with conventional double inversion-recovery (DIR) and motion-sensitive driven equilibrium (MSDE) preparation modules and to introduce a new three-dimensional (3D) T1-weighted magnetic resonance (MR) imaging sequence.Materials and Methods: Carotid artery wall imaging was performed in 10 healthy volunteers and 15 patients in accordance with an institutional review board-approved protocol. Two-dimensional (2D) turbo spin-echo (TSE) and 3D fast low-angle shot (FLASH) sequences served as readout modules. DANTE-prepared T1-, T2-, and proton density-weighted 2D TSE images, as well as T1- weighted 3D DANTE-prepared FLASH (hereafter, 3D DASH) images, were acquired in the region of the carotid artery bifurcation. For comparison, 2D DIR-prepared, 2D MSDE-prepared multicontrast TSE, and 3D MSDE-prepared FLASH (hereafter, 3D MERGE) MR images were also acquired. The effective contrast-to-noise ratio (CNReff) per unit time was calculated for all sequences. Paired t tests were performed to test within-group differences in vessel wall CNReff.Results: The CNReff of DANTE-prepared T1-, T2-, and proton density-weighted sequences was 27.3, 14.7, and 25.7 mm(-1)min-(1/2), respectively; this represented an improvement of approximately 25%-100% (P < .05) when compared with the CNReff attained with existing methods. The 3D DASH technique proved to be a fast (< 2 seconds per section) and high-spatial-resolution (0.6 mm isotropic) BB technique with higher (75%-100% improvement, P < .001) signal-to-noise ratio efficiency than the 3D MERGE technique.Conclusion: The DANTE-prepared multicontrast 2D BB technique is a promising new tool for MR imaging of carotid artery walls. Additionally, the 3D DASH sequence enables 3D high-spatial-resolution fast T1- weighted imaging of carotid artery walls. (C)RSNA, 2014