COVID-19 Disease Severity Risk Factors for Pediatric Patients in Italy
COVID-19 Disease Severity Risk Factors for Pediatric Patients in Italy
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DOI：
10.1542/peds.2020-009399
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发表时间：
2020-10-01
期刊：
影响因子：
8
通讯作者：
Pezzotti, Patrizio
中科院分区：
文献类型：
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作者：
Bellino, Stefania;Punzo, Ornella;Pezzotti, Patrizio
目的：了解老年儿童冠状病毒病(新冠肺炎)的流行病学和临床特征。方法：对截至2020年5月8日的全国新冠肺炎确诊病例监测系统资料进行分析。按年龄分组(0~1岁、2~6岁、7~12岁、13~18岁)总结受试者的人口学和临床特征，并用多水平(按地区分组)多因素Logistic回归模型评估疾病严重程度的危险因素。此外，还对儿童、成人和老年人进行了比较。结果：儿科患者3836例，占感染总数的1.8%(216305例)，中位年龄11岁，男性51.4%，住院13.3%，有基础疾病5.4%。32.4%的病例病情较轻，4.3%的病例病情较重，尤其是儿童
OBJECTIVES: To describe the epidemiological and clinical characteristics of coronavirus disease (COVID-19) pediatric patients aged METHODS: Data from the national case-based surveillance system of confirmed COVID-19 infections until May 8, 2020, were analyzed. Demographic and clinical characteristics of subjects were summarized by age groups (0-1, 2-6, 7-12, 13-18 years), and risk factors for disease severity were evaluated by using a multilevel (clustered by region) multivariable logistic regression model. Furthermore, a comparison among children, adults, and elderly was performed. RESULTS: Pediatric patients (3836) accounted for 1.8% of total infections (216 305); the median age was 11 years, 51.4% were male, 13.3% were hospitalized, and 5.4% presented underlying medical conditions. The disease was mild in 32.4% of cases and severe in 4.3%, particularly in children