AUTONOMIC EFFECTOR RESPONSES TO STIMULATION OF NUCLEUS FASTIGIUS
AUTONOMIC EFFECTOR RESPONSES TO STIMULATION OF NUCLEUS FASTIGIUS
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DOI：
10.1113/jphysiol.1970.sp009232
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发表时间：
1970-01-01
影响因子：
5.5
通讯作者：
DOWNMAN, CBB
中科院分区：
文献类型：
--
作者：
ACHARI, NK;DOWNMAN, CBB
1. 在麻醉的猫中，电刺激苛严核引起心血管反应、爪子的皮肤电反应和瞳孔扩张并引起鼻膜收缩。2. 心血管反应包括动脉压升高和周围血管收缩。脉压升高，心动过速。3. 交感神经阻滞药物的作用表明，颅尖刺激引起交感神经向心脏和周围血管放电。没有迷走神经活动改变的证据。4. 颅尖刺激可抑制因颈动脉窦扩张、迷走神经传入刺激或苯二胍引起的反射性心动过缓。5. 切断连接尖丘脑和下丘脑的神经通路后，可诱发尖丘脑和下丘脑对心血管反应的影响。6. 双侧分离颈动脉窦和迷走神经后，对神经刺激的压力反应仍然存在。
1. In anaesthetized cats electrical stimulation of the nucleus fastigius caused cardiovascular responses, electrodermal responses of the paws and pupil dilation with retraction of the nictitating membranes. 2. The cardiovascular responses included rise of arterial pressure and peripheral vasoconstriction. Increase of pulse pressure and tachycardia also occurred. 3. The effects of sympathetic blocking drugs indicate that fastigial stimulation causes sympathetic discharge to the heart and to the peripheral vessels. There was no evidence of alteration of vagal activity. 4. Fastigial stimulation inhibited reflex bradycardia due to carotid sinus distension, vagal afferent stimulation or phenyl diguanide. 5. Fastigial and hypothalamic influences on cardiovascular responses could be evoked after severing the nervous pathways connecting the two. 6. The pressor response to fastigial stimulation was still present after bilateral division of the carotid sinus and vagus nerves.