Continuous Metal-Organic Framework Biomineralization on Cellulose Nanocrystals: Extrusion of Functional Composite Filaments
Continuous Metal-Organic Framework Biomineralization on Cellulose Nanocrystals: Extrusion of Functional Composite Filaments
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DOI：
10.1021/acssuschemeng.8b06713
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发表时间：
2019-03-18
影响因子：
8.4
通讯作者：
Ejima, Hirotaka
中科院分区：
文献类型：
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作者：
Richardson, Joseph J.;Tardy, Blaise L.;Ejima, Hirotaka
近年来，围绕生物分子生长的金属有机骨架(MOF)已成为一种将天然材料和合成材料结合在一起的很有前途的方法。同时，纤维素纳米晶(CNCs)由于其生物衍生性质、高比表面积和高强度，已被用于形成广泛的可再生纳米和宏观材料。在这里，我们展示了MOF从CNCS表面连续成核，从而形成杂化水凝胶、气凝胶和多孔性组件，这些组件可以预加载或后加载功能货物。通过简单地混合CNCs和MOF前体，生物矿化被启动并持续进行，其中MOF同时覆盖和交联CNCs，覆盖范围广泛的CNCs和MOF前体浓度。此外，可以将碳纳米管挤出到预混合的MOF前驱体中，以产生可以预加载功能性酶或后加小荧光团的CNC-MOF长丝。总体而言，我们的方法能够实现对具有广泛应用前景的功能复合材料的快速结构控制。
Growing metal-organic frameworks (MOFs) around biomolecules has recently emerged as a promising method to combine natural and synthetic materials. In parallel, cellulose nanocrystals (CNCs) have found use for forming a wide range of renewable nano- and macroscopic materials because of their bio-derived nature, high surface area, and high strength. Herein, we demonstrate the continuous nucleation of MOFs from the surface of CNCs, thereby forming hybrid hydrogels, aerogels, and porous assemblies that can be pre- or postloaded with functional cargo. With simple mixing of CNCs with MOF precursors, the biomineralization is initiated and takes place continuously where the MOFs simultaneously coat and cross-link the CNCs across a wide range of CNC and MOF precursor concentrations. Additionally, CNCs can be extruded into the premixed MOF precursors to yield CNC-MOF filaments that can be preloaded with functional enzymes or postloaded with small fluorophores. Overall, our approach enables the rapid structural control of functional composites promising for a range of applications.