Enhancement of Surface Plasmon Resonance Sensing for DNA Hybridization Using Colloidal Au Attached Probe DNA.
Enhancement of Surface Plasmon Resonance Sensing for DNA Hybridization Using Colloidal Au Attached Probe DNA.
复制标题
使用胶体 Au 附着探针 DNA 增强 DNA 杂交的表面等离子共振传感。
DOI:
10.1246/cl.2002.190
复制
发表时间:
2002
影响因子:
1.6
通讯作者:
H. Misawa
中科院分区:
文献类型:
--
作者:
A. Yamaguchi;S. Juodkazis;S. Matsuo;H. Misawa
In this study, we demonstrate that the Au particle modified probe DNA monolayer can enhance the surface plasmon resonance (SPR) signal for measuring hybridization of unlabeled DNA molecules. The Au particles adsorbed on single stranded (ss)- and double stranded (ds)-DNA monolayers have different optical interaction with surface of Au thin film, and this difference induces the enhancement of the SPR signal.