The EEG and Differential Diagnosis in Psychogeriatrics
The EEG and Differential Diagnosis in Psychogeriatrics
复制标题
老年心理病学中的脑电图和鉴别诊断
DOI：
10.1192/bjp.135.2.156
复制
发表时间：
1979
影响因子：
10.5
通讯作者：
C. Ongley
中科院分区：
文献类型：
--
作者：
K. P. O'Connor;J. Shaw;C. Ongley
摘要基于脑电一致性的皮质地形图测量，提出了一种区分老年性、动脉硬化性痴呆和抑郁状态的脑功能障碍的模型。对24例临床确诊为老年性痴呆、老年性动脉硬化或抑郁症的老年患者，从中央、顶叶、枕叶和颞区记录双极脑电。计算了在睁眼、闭眼和光刺激期间记录的20秒的功率谱和相干谱。据报道，在权力和凝聚力方面，两组都存在显著差异。所有通道的功率结果都是一致的，但相干性值随来源的不同而显著不同。组间最好的判别器是右侧顶叶和颞叶来源之间的脑电一致性估计。临床症状与脑电一致性之间的相关性支持组间辨别的方向。脑电相干功能被认为是精神病学神经功能病理学的一种潜在的测量方法。
Summary A model for differentiating cerebral dysfunction in senile, arteriosclerotic dementia, and depressive states is proposed on the basis of electrocortical topographic measures of EEG coherence. Bipolar EEGs were recorded from central, parietal, occipital and temporal areas in 24 elderly patients with a firm clinical diagnosis of senile dementia, senile arteriosclerosis or depression. Power and coherence spectra were computed on 20 second epochs recorded during eyes open, eyes closed and photic stimulation. Significant group differences were reported in both power and coherence measures. Power results were uniform for all channels but coherence values differed significantly with derivation. The best discriminator between groups was EEG coherence estimates between right parietal and temporal derivation. Correlations between clinical symptomatology and EEG coherence supported the direction of the discrimination between groups. The EEG coherence function is discussed as a potential measure of neuro-functional pathology in psychiatry.