Enhancement of Dose Response and Nuclear Magnetic Resonance Image of PAGAT Polymer Gel Dosimeter by Adding Silver Nanoparticles.
Enhancement of Dose Response and Nuclear Magnetic Resonance Image of PAGAT Polymer Gel Dosimeter by Adding Silver Nanoparticles.
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DOI：
10.1371/journal.pone.0168737
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Sedghi A
中科院分区：
文献类型：
--
作者：
Sabbaghizadeh R;Shamsudin R;Deyhimihaghighi N;Sedghi A
在本研究中，常氧聚丙烯酰胺明胶和四羟甲基氯化膦（PAGAT）聚合物凝胶剂量计的合成与不存在的银（Ag）纳米粒子。Ag纳米颗粒的量从1到3 ml变化，浓度为3.14 g/l，从而形成两种类型的PAGAT聚合物凝胶剂量计，然后用由1.25 MeV 60 Co γ射线产生的6到25戈伊照射它们。在这个范围内，主要的伽马射线与物质的相互作用是通过康普顿散射效应，因为光电吸收效应减弱。当评价剂量计的聚合时采用MRI，并且通过光密度计确定MRI膜的灰度。随后的光密度分析表明，聚合的程度随着吸收剂量的增加而增加，而剂量计内的渗透深度的增加具有相反的效果。此外，一个显着增加的光密度剂量响应（11.82%），注意到剂量计含有2毫升银纳米粒子。
In the present study, the normoxic polyacrylamide gelatin and tetrakis hydroxy methyl phosphoniun chloride (PAGAT) polymer gel dosimeters were synthesized with and without the presence of silver (Ag) nanoparticles. The amount of Ag nanoparticles varied from 1 to 3 ml with concentration 3.14 g/l, thus forming two types of PAGAT polymer gel dosimeters before irradiating them with 6 to 25 Gy produced by 1.25-MeV 60Co gamma rays. In this range, the predominant gamma ray interaction with matter is by Compton scattering effect, as the photoelectric absorption effect diminishes. MRI was employed when evaluating the polymerization of the dosimeters and the gray scale of the MRI film was determined via an optical densitometer. Subsequent analyses of optical densities revealed that the extent of polymerization increased with the increase in the absorbed dose, while the increase of penetration depth within the dosimeters has a reverse effect. Moreover, a significant increase in the optical density-dose response (11.82%) was noted for dosimeters containing 2 ml Ag nanoparticles.