A history of influenza
A history of influenza
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DOI：
10.1046/j.1365-2672.2001.01492.x
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发表时间：
2001-10-01
影响因子：
4
通讯作者：
Potter, CW
中科院分区：
文献类型：
--
作者：
Potter, CW
流感流行和大流行的历史可以比较准确地追溯到过去三百年，而在此之前则不太确定，从历史来看，很明显，在大多数年份，世界上的某个地方都会发生疫情。每年的流行病是由于抗原漂移造成的；每隔10至50年发生一次的大流行是由于病毒重组产生新的病毒亚型。在过去100年中，没有采取任何措施来影响流行病和大流行病的复发模式；我们的过去清楚地表明了我们在新世纪的未来。本文对这一过去的经验进行了回顾。
From the history of influenza epidemics and pandemics, which can be traced back with some accuracy for the past three hundred years, and with less certainty before this time, it is apparent that outbreaks occur somewhere in the world in most years. Annual epidemics are due to antigenic drift; and pandemics, occurring at 10 to 50 years intervals, are due to new virus subtypes resulting from virus reassortment. Nothing has been introduced during the past 100 years to affect the recurrent pattern of epidemics and pandemics; and our future in the new century is clearly indicated by our past. This past experience is reviewed in the present paper.