Contrast Staining may be Associated with Intracerebral Hemorrhage but Not Functional Outcome in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy
Contrast Staining may be Associated with Intracerebral Hemorrhage but Not Functional Outcome in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy
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DOI：
10.14336/ad.2018.0807
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发表时间：
2019-08-01
影响因子：
7.4
通讯作者：
Ji, Xunming
中科院分区：
文献类型：
--
作者：
An, Hong;Zhao, Wenbo;Ji, Xunming
评价接受血管内血栓切除术（ET）治疗的急性缺血性卒中（AIS）中国患者的介入后造影剂染色（PICS）发生率，并研究PICS与功能结局和脑出血（ICH）的潜在相关性。本观察性研究基于单中心前瞻性登记研究。本研究招募了2013年1月至2017年2月接受ET的AIS患者。所有患者在ET后12至24小时进行头部双能量CT（DECT）扫描。主要结局是PICS的发生率。次要结局为总ICH、症状性ICH（sICH）、3个月功能结局和长期功能结局。本研究入组了180例患者。基于介入后CT扫描，在50例患者（28%）中检测到PICS。我们首先使用基本的统计学分析，结果显示，PICS患者的总ICH（60% vs. 25%，p< 0.001）和sICH（18% vs. 8%，p=0.044）的发生率均高于无PICS患者，且无残疾（mRS）的患者较少
To evaluate the incidence of post-interventional contrast staining (PICS) in acute ischemic stroke (AIS) Chinese patients who were treated with endovascular thrombectomy (ET) and investigate potential association of PICS with functional outcome and intracerebral hemorrhage (ICH). This observational study was based on a single-center prospective registry study. AIS patients who underwent ET from January 2013 to February 2017 were recruited into this study. All patients had dual-energy CT (DECT) scan of the head at 12 to 24 hours post-ET. The primary outcome was the incidence of PICS. Secondary outcomes were total ICH, symptomatic ICH (sICH), 3-month functional outcome, and long-term functional outcome. One hundred and eighty patients were enrolled in this study. PICS was detected in 50 patients (28%) based on the post-interventional CT scan. We first used basic statistical analyses, showing that the incidence of both total ICH (60% vs. 25%, p< 0.001) and sICH (18% vs. 8%, p=0.044) were higher in patients with PICS than those without, and fewer patients achieved no disability (mRS