STAGING OF SUSPECTED BREAST-CANCER - EFFECT OF MR-IMAGING AND MR-GUIDED BIOPSY

STAGING OF SUSPECTED BREAST-CANCER - EFFECT OF MR-IMAGING AND MR-GUIDED BIOPSY
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DOI:
10.1148/radiology.196.1.7784554
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发表时间:
1995-07-01
期刊:
影响因子:
19.7
通讯作者:
ROSATO, EF
ROSATO, EF
中科院分区:
医学1区
文献类型:
--
作者:
OREL, SG;SCHNALL, MD;ROSATO, EF

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目的:探讨对比剂增强磁共振(MR)成像在钼靶或临床可疑肿瘤患者乳腺癌分期中的作用。材料与方法:对176例可疑乳腺钼靶或可触及异常的患者,在切除活检前行1.5T磁共振乳腺成像。对经活检证实或推测为乳腺癌的患者的影像诊断研究进行综述。结果:64例患者符合研究标准。磁共振成像能够检测出所有57例浸润性乳腺癌和15例原位癌中的9例。在22例患者(34%)中,MR成像显示了一个或多个在乳房X光检查中看不到的癌症,其中13例(20%)是未被怀疑的多灶性或弥漫性疾病。7例(11%)患者的临床分期和随后的治疗发生改变,原因是MR成像的敏感性高于钼靶摄影。结论:MR成像可以发现可疑乳腺癌患者的钼靶和临床隐匿性癌灶。
PURPOSE: To investigate the effect of contrast material-enhanced magnetic resonance (MR) imaging on staging of breast cancer in patients with mammographically or clinically suspected tumor.MATERIALS AND METHODS: One hundred seventy-six patients underwent breast MR imaging at 1.5 T before excisional biopsy of a suspicious mammographic or palpable abnormality. Diagnostic imaging studies in patients with biopsy-proved or presumed breast carcinoma were reviewed.RESULTS: Sixty-four patients met the study criteria. MR imaging enabled detection of all 57 invasive breast cancers and nine of 15 in situ cancers. In 22 patients (34%), MR imaging depicted one or more cancers not visible at mammography, 13 (20%) of which were unsuspected multifocal or diffuse disease. As a result of the increased sensitivity of MR imaging compared with that of mammography, clinical staging and subsequent treatment were altered in seven patients (11%).CONCLUSION: MR imaging allows detection of mammographically and clinically occult foci of carcinoma in patients with suspected breast cancer.