Feasibility Study of Alanine Dosimeter for Carbon-Beam Dosimetry
Feasibility Study of Alanine Dosimeter for Carbon-Beam Dosimetry
复制标题
丙氨酸剂量计碳束剂量测定的可行性研究
DOI：
10.1007/978-981-10-9023-3_104
复制
发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Fukumura A.
中科院分区：
文献类型：
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作者：
Yamaguchi H.;Shimizu M.;Morishita Y.;Hirayama K.;Satou Y.;Kato M.;Kurosawa T.;Tanaka T.;Saito N.;Sakama M.;Fukumura A.
丙氨酸剂量计是用于测量千灰度级剂量和放射治疗级剂量的有用工具。日本国家计量研究所正计划为碳束治疗开发一种剂量测量服务。本研究的目的是验证丙氨酸剂量计可用于碳束剂量测定。我们用~（60）Co-γ射线和碳束照射丙氨酸剂量计，剂量范围为10-30戈伊。对于γ射线照射，丙氨酸剂量计放置在5 g cm− 2水模体中。对于碳束照射，使用290 meV/u碳离子的扩展布拉格峰，并且剂量计位于峰区域的中心。在碳束照射下获得的丙氨酸光谱与γ射线照射下的光谱几乎相同。用碳束照射的丙氨酸剂量计显示出比在相同剂量的γ射线照射下获得的信号小的信号。丙氨酸信号随着剂量的增加而增加，对于γ射线和碳束照射两者，在整个剂量范围内。这一结果表明，丙氨酸剂量计有潜力的碳束剂量测定。
Alanine dosimeters are useful tools for measuring both kilo-gray level doses and radiation therapy level doses. The National Metrology Institute of Japan is planning to develop a dose measurement service for carbon-beam therapy. The purpose of this study was to verify that the alanine dosimeter could be used for carbon-beam dosimetry. We irradiated the alanine dosimeter with60Co-gamma rays and a carbon beam using a range of 10–30 Gy. For the gamma-ray irradiation, the alanine dosimeter was placed in a 5 g cm−2water phantom. For the carbon-beam irradiation, the spread out Bragg peak of the 290 meV/u carbon ion was used, and the dosimeter was located at the centre of the peak region. The alanine spectra obtained under the carbon-beam irradiation were almost the same as the spectra under the gamma-ray irradiation. The alanine dosimeter irradiated with the carbon beam show a smaller signal than that obtained under the gamma-ray irradiation for the same dose. The alanine signal increased as the dose increased over the entire dosage range for both the gamma-ray and carbon-beam irradiation. This result suggests that the alanine dosimeter has potential for carbon-beam dosimetry.